The dark side of the moon: AKT as a tumor suppressor in the liver?
Xin Chen, Diego F. Calvisi – 12 August 2016
Hepatitis C virus plays hide and seek with neutralizing antibodies
Dorothea Bankwitz, Thomas Pietschmann – 12 August 2016
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Babak Banan, Yiing Lin, William Chapman – 12 August 2016
Outcome of living donor liver transplantation using right liver allografts with multiple arterial supply
Kyo Won Lee, Sanghoon Lee, Jeungmin Huh, Chan Woo Cho, Nuri Lee, Hye Seung Kim, Kyunga Kim, Jong Man Kim, Gyu Seong Choi, Choon Hyuck David Kwon, Jae‐Won Joh, Suk‐Koo Lee – 12 August 2016 – A right liver graft with multiple hepatic artery (HA) stumps can be found in approximately 5% of living donor liver transplantation (LDLT) using a right lobe graft. From January 2000 to June 2014, 1149 patients underwent LDLT procedures. Thirty patients with LDLT using a right lobe graft with multiple HA stumps and 149 patients with LDLT using a right lobe graft with a single HA stump were enrolled.
Roadmap for improving patient and graft survival in the next 10 years
Michael R. Charlton – 12 August 2016
Novel educational interventions in residency increase knowledge of chronic liver disease and career interest in hepatology
Adam E. Mikolajczyk, Jeanne M. Farnan, John F. McConville, Donald M. Jensen, K. Gautham Reddy, Helen S. Te, Nancy Reau, Andrew I. Aronsohn – 10 August 2016 – There is an increasing burden of chronic liver disease (CLD) in the United States but a significant shortage of hepatologists. Thus, it is necessary to develop new recruitment strategies to the field of hepatology as well as ensure that non‐gastroenterology‐trained physicians are able to capably assist in the care of CLD.
Robotic liver donor right hepatectomy: A pure, minimally invasive approach
Po‐Da Chen, Chao‐Ying Wu, Rey‐Heng Hu, Cheng‐Maw Ho, Po‐Huang Lee, Hong‐Shiee Lai, Ming‐Tsan Lin, Yao‐Ming Wu – 10 August 2016 – Right hepatectomy for a living liver donor via a pure minimally invasive approach is a challenging procedure and only a few cases have been reported. Between May 2013 and August 2015, 13 patients underwent robotic living donor right hepatectomy in our institute, and 54 patients received open surgery. In this series, no conversion was conducted for robotic donor right hepatectomy.
The brain gets its say: Hepatic encephalopathy and its evolving role in transplant priority
Jasmohan S. Bajaj, Patrick S. Kamath – 10 August 2016
Graft‐to‐recipient weight ratio threshold adjusted to the model for end‐stage liver disease score for living donor liver transplantation
Altan Alim, Yalcin Erdogan, Yildiray Yuzer, Yaman Tokat, Arzu Oezcelik – 10 August 2016 – The graft‐to‐recipient weight ratio (GRWR) is an important selection criterion for living donor liver transplantation (LDLT). The generally accepted threshold is known to be 0.8%. We believe that this threshold can be reduced under certain conditions. The aim of this study was to evaluate the results of these patients with GRWR < 0.8%. Between 2004 and 2015, 649 patients underwent right lobe LDLT for end‐stage liver disease in adult patients. All recipients who had GRWR < 0.8% were identified.
Encapsulated platelets modulate kupffer cell activation and reduce oxidative stress in a model of acute liver failure
Mónica Luján López, Carolina Uribe‐Cruz, Alessandro Osvaldt, Carlos Oscar Kieling, Laura Simon, Santiago Tobar, Michael Andrades, Ursula Matte – 10 August 2016 – Acute liver failure (ALF) is characterized by massive hepatocyte cell death. Kupffer cells (KC) are the first cells to be activated after liver injury. They secrete cytokines and produce reactive oxygen species, leading to apoptosis of hepatocytes. In a previous study, we showed that encapsulated platelets (PLTs) increase survival in a model of ALF. Here, we investigate how PLTs exert their beneficial effect.