Liver alkaline phosphatase: A missing link between choleresis and biliary inflammation

Raoul Poupon – 20 January 2015 – Several lines of evidence show that serum alkaline phosphatase (AP) is not only a signpost of cholestasis but also a surrogate marker of the severity of primary biliary cirrhosis and primary sclerosing cholangitis. In the present opinion article, we review and discuss the putative role of liver AP in health and in cholestatic diseases.

Safety and efficacy of splenic artery embolization for portal hyperperfusion in liver transplant recipients: A 5‐year experience

Naftali Presser, Cristiano Quintini, Cynthia Tom, Weiping Wang, Qiang Liu, Teresa Diago‐Uso, Masato Fujiki, Charles Winans, Dympna Kelly, Federico Aucejo, Koji Hashimoto, Bijan Eghtesad, Charles Miller – 20 January 2015 – Severe portal hyperperfusion (PHP) after liver transplantation has been shown to cause intrahepatic arterial vasoconstriction secondary to increased adenosine washout (hepatic artery buffer response). Clinically, posttransplant PHP can cause severe cases of refractory ascites and hydrothorax.

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