Model for end‐stage liver disease‐based allocation system: On the right path, but not there yet
Ângelo Zambam de Mattos, Angelo Alves de Mattos – 22 March 2015
Activation of sphingosine kinase 2 by endoplasmic reticulum stress ameliorates hepatic steatosis and insulin resistance in mice
Su‐Yeon Lee, In‐Kyung Hong, Bo‐Rahm Kim, Soon‐Mi Shim, Jae Sung Lee, Hui‐Young Lee, Cheol Soo Choi, Bo‐Kyung Kim, Tae‐Sik Park – 22 March 2015 – The endoplasmic reticulum (ER) is the principal organelle in the cell for protein folding and trafficking, lipid synthesis, and cellular calcium homeostasis. Perturbation of ER function results in activation of the unfolded protein response (UPR) and is implicated in abnormal lipid biosynthesis and development of insulin resistance.
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Daniel Pineda‐Tenor, Mónica García‐Álvarez, María A. Jiménez‐Sousa, Amanda Fernández‐Rodríguez, Salvador Resino – 21 March 2015
Liver inflammation abrogates immunological tolerance induced by Kupffer cells
Felix Heymann, Julia Peusquens, Isis Ludwig‐Portugall, Marlene Kohlhepp, Can Ergen, Patricia Niemietz, Christian Martin, Nico van Rooijen, Jordi C. Ochando, Gwendalyn J. Randolph, Tom Luedde, Florent Ginhoux, Christian Kurts, Christian Trautwein, Frank Tacke – 21 March 2015
Relationship between vitamin D status and response to hepatitis C virus therapy
Matthew T. Kitson, Christoph Sarrazin, Pierluigi Toniutto, Stuart K. Roberts – 21 March 2015
Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B
De‐Ke Jiang, Xiao‐Pin Ma, Hongjie Yu, Guangwen Cao, Dong‐Lin Ding, Haitao Chen, Hui‐Xing Huang, Yu‐Zhen Gao, Xiao‐Pan Wu, Xi‐Dai Long, Hongxing Zhang, Youjie Zhang, Yong Gao, Tao‐Yang Chen, Wei‐Hua Ren, Pengyin Zhang, Zhuqing Shi, Wei Jiang, Bo Wan, Hexige Saiyin, Jianhua Yin, Yuan‐Feng Zhou, Yun Zhai, Pei‐Xin Lu, Hongwei Zhang, Xiaoli Gu, Aihua Tan, Jin‐Bing Wang, Xian‐Bo Zuo, Liang‐Dan Sun, Jun O. Liu, Qing Yi, Zengnan Mo, Gangqiao Zhou, Ying Liu, Jielin Sun, Yin Yao Shugart, S.
Acute‐on‐chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults
Yu Shi, Ying Yang, Yaoren Hu, Wei Wu, Qiao Yang, Min Zheng, Shun Zhang, Zhaojun Xu, Yihua Wu, Huadong Yan, Zhi Chen – 20 March 2015 – Patients with acute‐on‐chronic liver failure (ACLF) represent a heterogeneous population. The aim of the study is to identify distinct groups according to the etiologies of precipitating events. A total of 405 ACLF patients were identified from 1,361 patients with cirrhosis with acute decompensation and categorized according to the types of acute insults.
Acute‐on‐chronic liver failure precipitated by hepatic injury is distinct from that precipitated by extrahepatic insults
Yu Shi, Ying Yang, Yaoren Hu, Wei Wu, Qiao Yang, Min Zheng, Shun Zhang, Zhaojun Xu, Yihua Wu, Huadong Yan, Zhi Chen – 20 March 2015 – Patients with acute‐on‐chronic liver failure (ACLF) represent a heterogeneous population. The aim of the study is to identify distinct groups according to the etiologies of precipitating events. A total of 405 ACLF patients were identified from 1,361 patients with cirrhosis with acute decompensation and categorized according to the types of acute insults.
Renal safety of intravenous gadolinium‐enhanced magnetic resonance imaging in patients awaiting liver transplantation
Katherine M. Shaffer, Mehul R. Parikh, Thomas M. Runge, Sebastian D. Perez, Sonali S. Sakaria, Ram M. Subramanian – 18 March 2015 – Renal dysfunction in cirrhosis carries a high morbidity and mortality. Given the potential risk of contrast‐induced nephropathy associated with iodinated intravenous contrast used in computed tomography (CT), alternate contrast modalities for abdominal imaging in liver transplant candidates need to be examined.
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Brian S. Zuckerbraun, Changchun Cai, Timothy R. Billiar – 17 March 2015