Yes‐associated protein 1 and transcriptional coactivator with PDZ‐binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma

Yun‐Yong Park, Bo Hwa Sohn, Randy L. Johnson, Myoung‐Hee Kang, Sang Bae Kim, Jae‐Jun Shim, Lingegowda S. Mangala, Ji Hoon Kim, Jeong Eun Yoo, Cristian Rodriguez‐Aguayo, Sunila Pradeep, Jun Eul Hwang, Hee‐Jin Jang, Hyun‐Sung Lee, Rajesha Rupaimoole, Gabriel Lopez‐Berestein, Woojin Jeong, Inn Sun Park, Young Nyun Park, Anil K. Sood, Gordon B. Mills, Ju‐Seog Lee – 21 September 2015 – Metabolic activation is a common feature of many cancer cells and is frequently associated with the clinical outcomes of various cancers, including hepatocellular carcinoma.

Split liver transplantation: Report of right and left graft outcomes from a multicenter Argentinean group

Esteban Halac, Marcelo Dip, Emilio Quiñonez, Fernando Alvarez, Johana Leiva Espinoza, Pablo Romero, Franco Nievas, Rafael Maurette, Carlos Luque, Daniel Matus, Paz Surraco, Martin Fauda, Lucas McCormack, Francisco J. Mattera, Gabriel Gondolesi, Oscar Imventarza – 15 September 2015 – Grafts from split livers (SLs) constitute an accepted approach to expand the donor pool. Over the last 5 years, most Argentinean centers have shown significant interest in increasing the use of this technique.

Conversion of once‐daily extended‐release tacrolimus is safe in stable liver transplant recipients: A randomized prospective study

Jong Man Kim, Choon Hyuck David Kwon, Jae‐Won Joh, Dong Hyun Sinn, Sanghoon Lee, Gyu‐Seong Choi, Suk‐Koo Lee – 11 September 2015 – Simplifying the therapeutic regimen of liver transplantation (LT) recipients may help prevent acute rejection and graft failure. The present study aimed to evaluate the efficacy and safety of conversion from twice‐daily tacrolimus to once‐daily extended‐release tacrolimus under concurrent mycophenolate mofetil therapy in stable LT recipients.

Primary prophylaxis of variceal bleeding in children and the role of MesoRex Bypass: Summary of the Baveno VI Pediatric Satellite Symposium

Benjamin L. Shneider, Jean de Ville de Goyet, Daniel H. Leung, Anshu Srivastava, Simon C. Ling, Mathieu Duché, Patrick McKiernan, Riccardo Superina, Robert H. Squires, Jaime Bosch, Roberto Groszmann, Shiv K. Sarin, Roberto de Franchis, George V. Mazariegos – 11 September 2015 – Approaches to the management of portal hypertension and variceal hemorrhage in pediatrics remain controversial, in large part because they are not well informed by rigorous clinical studies. Fundamental biological and clinical differences preclude automatic application of approaches used for adults to children.

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