Macrosteatotic and nonmacrosteatotic grafts respond differently to intermittent hepatic inflow occlusion: Comparison of recipient survival

Sangbin Han, Gyu‐Seong Choi, Jong Man Kim, Ji Hye Kwon, Hyo‐Won Park, Gaabsoo Kim, Choon Hyuck David Kwon, Mi Sook Gwak, Justin Sangwook Ko, Jae‐Won Joh – 17 February 2015 – Intermittent hepatic inflow occlusion (IHIO) during liver graft procurement is known to confer protection against graft ischemia/reperfusion injury and thus may benefit the recipient's outcome. We evaluated whether the protective effect of IHIO differs with the presence of macrosteatosis (MaS) and with an increase or decrease in the cumulative occlusion time.

The significance of nonobstructive sinusoidal dilatation of the liver: Impaired portal perfusion or inflammatory reaction syndrome

Chiara Marzano, Dominique Cazals‐Hatem, Pierre‐Emmanuel Rautou, Dominique‐Charles Valla – 13 February 2015 – Sinusoidal dilatation found in the absence of an impaired sinusoidal blood outflow has been so far of unclear significance. Sinusoidal dilatation may actually be a nonspecific feature of impaired portal venous blood inflow, whatever the cause, or a feature of severe systemic inflammatory reaction syndrome, whatever the cause. Sinusoidal dilatation is mainly located in the centrilobular area even in the absence of an outflow block.

The significance of nonobstructive sinusoidal dilatation of the liver: Impaired portal perfusion or inflammatory reaction syndrome

Chiara Marzano, Dominique Cazals‐Hatem, Pierre‐Emmanuel Rautou, Dominique‐Charles Valla – 13 February 2015 – Sinusoidal dilatation found in the absence of an impaired sinusoidal blood outflow has been so far of unclear significance. Sinusoidal dilatation may actually be a nonspecific feature of impaired portal venous blood inflow, whatever the cause, or a feature of severe systemic inflammatory reaction syndrome, whatever the cause. Sinusoidal dilatation is mainly located in the centrilobular area even in the absence of an outflow block.

Improvement of predictive models of risk of disease progression in chronic hepatitis C by incorporating longitudinal data

Monica A. Konerman, Yiwei Zhang, Ji Zhu, Peter D.R. Higgins, Anna S.F. Lok, Akbar K. Waljee – 12 February 2015 – Existing predictive models of risk of disease progression in chronic hepatitis C have limited accuracy. The aim of this study was to improve upon existing models by applying novel statistical methods that incorporate longitudinal data. Patients in the Hepatitis C Antiviral Long‐term Treatment Against Cirrhosis trial were analyzed.

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