Lingling Zhang, Leiming Liu, Zhiyong He, Guangbing Li, Junping Liu, Zhangfa Song, Hongchuan Jin, Karl Lenhard Rudolph, Huayu Yang, Yilei Mao, Lianfeng Zhang, Hongbing Zhang, Zhicheng Xiao, Zhenyu Ju – 23 February 2015 – The liver possesses extraordinary regenerative capacity in response to injury. However, liver regeneration (LR) is often impaired in disease conditions. Wild‐type p53‐induced phosphatase 1 (Wip1) is known as a tumor promoter and enhances cell proliferation, mainly by deactivating antioncogenes. However, in this work, we identified an unexpected role of Wip1 in LR.

Zobair M. Younossi, Yushan Jiang, Nathaniel J. Smith, Maria Stepanova, Rachel Beckerman – 23 February 2015 – Patients with chronic hepatitis C (CHC) exhibit reduced work productivity owing to their disease. Historically, most regimens indicated for CHC genotype 1 (GT1) patients were administered with pegylated interferon (Peg‐IFN) and/or ribavirin (RBV), which further compromised work productivity during treatment.

Jean‐François Dufour – 20 February 2015

Jean‐François Dufour – 20 February 2015

Michael F. Sorrell – 18 February 2015

Michael R. Marvin, Nicole Ferguson, Robert M. Cannon, Christopher M. Jones, Guy N. Brock – 18 February 2015 – Multiple studies have demonstrated an advantage for hepatocellular carcinoma (HCC) patients under the current liver allocation system, such that the United Network for Organ Sharing (UNOS) recently voted in support of a proposal to delay granting Model for End‐Stage Liver Disease (MELD) exception points to all HCC patients for 6 months, independently of a candidate's native MELD score or alpha‐fetoprotein (AFP) level.

Edgar N. Tafaleng, Souvik Chakraborty, Bing Han, Pamela Hale, Wanquan Wu, Alejandro Soto‐Gutierrez, Carol A. Feghali‐Bostwick, Andrew A. Wilson, Darrell N. Kotton, Masaki Nagaya, Stephen C. Strom, Jayanta Roy‐Chowdhury, Donna B. Stolz, David H. Perlmutter, Ira J. Fox – 18 February 2015 – In the classical form of α1‐antitrypsin deficiency (ATD), aberrant intracellular accumulation of misfolded mutant α1‐antitrypsin Z (ATZ) in hepatocytes causes hepatic damage by a gain‐of‐function, “proteotoxic” mechanism.

Francis Y. Yao, Neil Mehta, Jennifer Flemming, Jennifer Dodge, Bilal Hameed, Oren Fix, Ryutaro Hirose, Nicholas Fidelman, Robert K. Kerlan, John P. Roberts – 18 February 2015 – We report on the long‐term intention‐to‐treat (ITT) outcome of 118 patients with hepatocellular carcinoma (HCC) undergoing downstaging to within Milan/United Network for Organ Sharing T2 criteria before liver transplantation (LT) since 2002 and compare the results with 488 patients listed for LT with HCC meeting T2 criteria at listing in the same period.

Francis Y. Yao, Neil Mehta, Jennifer Flemming, Jennifer Dodge, Bilal Hameed, Oren Fix, Ryutaro Hirose, Nicholas Fidelman, Robert K. Kerlan, John P. Roberts – 18 February 2015 – We report on the long‐term intention‐to‐treat (ITT) outcome of 118 patients with hepatocellular carcinoma (HCC) undergoing downstaging to within Milan/United Network for Organ Sharing T2 criteria before liver transplantation (LT) since 2002 and compare the results with 488 patients listed for LT with HCC meeting T2 criteria at listing in the same period.

Saman Nikeghbalian, Alireza Shamsaeefar, Ahad Eshraghian, Mohsen Reza Mansoorian, Kourosh Kazemi, Bita Geramizadeh, Seyed Ali Malek‐Hosseini – 17 February 2015