Central obesity induces a greater risk of hepatocellular carcinoma than general obesity
Qing Pang, Jing Yao Zhang, Kai Qu, Si Dong Song, Su Shun Liu, Chang Liu – 24 December 2014
Ezrin finds its groove in cholangiocytes
Laura Fouassier, Romina Fiorotto – 24 December 2014
Evidence against a role of serotonin in liver regeneration in humans
Edris M. Alkozai, Martijn van Faassen, Ido P. Kema, Robert J. Porte, Ton Lisman – 24 December 2014
Farnesoid X receptor–induced lysine‐specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity
Young‐Chae Kim, Sungsoon Fang, Sangwon Byun, Sunmi Seok, Byron Kemper, Jongsook Kim Kemper – 24 December 2014 – Bile acids (BAs) function as endocrine signaling molecules that activate multiple nuclear and membrane receptor signaling pathways to control fed‐state metabolism. Since the detergent‐like property of BAs causes liver damage at high concentrations, hepatic BA levels must be tightly regulated.
Reply
Patrick Starlinger, Christine Brostjan, Thomas Gruenberger – 24 December 2014
Low risk of liver decompensation among human immunodeficiency virus/hepatitis C virus–coinfected patients with mild fibrosis in the short term
Juan Macías, María Mancebo, Manuel Márquez, Dolores Merino, Francisco Téllez, Antonio Rivero, Miguel A. von Wichmann, Luis F. López‐Cortés, Nicolás Merchante, Jesús Santos, Miguel Raffo, Montserrat Pérez‐Pérez, Ángela Camacho, Jose A. Iribarren, Juan A. Pineda – 24 December 2014 – Liver fibrosis is used to make decisions about the timing of therapy against hepatitis C virus (HCV) in routine clinical practice, which should be based on the short‐term likelihood of liver decompensations.
Prometheus and progenitors
Anna Mae Diehl – 24 December 2014
Biochemical markers, liver biopsy, or magnetic resonance elastography to detect or exclude advanced fibrosis in patients with nonalcoholic fatty liver disease
Huseyin Kayadibi, Erdim Sertoglu, Metin Uyanik – 24 December 2014
Recombinant adeno‐associated virus–mediated inhibition of microRNA‐21 protects mice against the lethal schistosome infection by repressing both IL‐13 and transforming growth factor beta 1 pathways
Xing He, Jun Xie, Dongmei Zhang, Qin Su, Xue Sai, Ruipu Bai, Chao Chen, Xufeng Luo, Guangping Gao, Weiqing Pan – 24 December 2014 – Schistosomiasis is a serious parasitic disease in humans, which can lead to liver fibrosis and death. Accumulating evidence indicated that targeting the deregulated microRNAs (miRNAs) could mitigate disease outcomes.
The “dose” of exercise and its effects beyond weight loss
Mary E. Rinella – 24 December 2014