Systems biological analyses reveal the hepatitis C virus (HCV)‐specific regulation of hematopoietic development

Victoria M. Velazquez, Luke S. Uebelhoer, Manoj Thapa, Chris C. Ibegbu, Cynthia Courtney, Steven E. Bosinger, Joseph F. Magliocca, Andrew B. Adams, Allan D. Kirk, Stuart J. Knechtle, Daniel Kalman, Mehul S. Suthar, Arash Grakoui – 21 October 2014 – Chronic liver disease is characterized by the liver enrichment of myeloid dendritic cells (DCs). To assess the role of disease on myelopoiesis, we utilized a systems biology approach to study development in liver‐resident cells expressing stem cell marker CD34.

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