National survey of adult transplant hepatologists on the pediatric‐to‐adult care transition after liver transplantation

Madeleine R. Heldman, Min‐Woong Sohn, Elisa J. Gordon, Zeeshan Butt, Saeed Mohammed, Estella M. Alonso, Josh Levitsky – 6 November 2014 – Adult transplant hepatologists face challenges in providing care to young adults who received liver transplants during childhood. Because prior studies have focused mainly on pediatric providers, understanding these issues from the perspective of the adult hepatologist may provide novel insights and identify key barriers to care in this population.

Hepatic artery stenosis after liver transplantation: Is endovascular treatment always necessary?

Carlo Pulitano, David Joseph, Charbel Sandroussi, Deborah Verran, Simone I. Strasser, Nicholas A. Shackel, Geoffrey W. McCaughan, Michael Crawford – 6 November 2014 – Hepatic artery stenosis (HAS) is thought to predispose patients to biliary complications secondary to ischemic injury. Despite this, the clinical significance of HAS remains poorly defined. The aims of this study were to determine the prevalence and outcomes of HAS and to define which patients might benefit from endovascular treatment.

Competition in liver transplantation: Helpful or harmful?

Reza F. Saidi, Moaven Razavi, A. Benedict Cosimi, Dicken S. C. Ko – 5 November 2014 – Improved outcomes of liver transplantation have led to increases in the numbers of US transplant centers and candidates on the list. The resultant and ever‐expanding organ shortage has created competition among centers, especially in regions with multiple liver transplant programs. Multiple reports now document that competition among the country's transplant centers has led to the listing of increasingly high‐risk patients and the utilization of more marginal liver allografts.

The clinical course of cirrhosis: The importance of multistate models and competing risks analysis

Peter Jepsen, Hendrik Vilstrup, Per Kragh Andersen – 5 November 2014 – Multistate models are models of disease progression that, for a patient group, define multiple outcome events, each of which may affect the time to develop another outcome event. Multistate models are highly relevant for studies of patients with cirrhosis; both the classical perception of cirrhosis as either compensated or decompensated and the recent, more complex models of cirrhosis progression are multistate models.

Hemostatic status in liver transplantation: Association between preoperative procoagulants/anticoagulants and postoperative hemorrhaging/thrombosis

Nobuhisa Akamatsu, Yasuhiko Sugawara, Akiko Nakazawa, Yujiro Nishioka, Junichi Kaneko, Taku Aoki, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo – 5 November 2014 – The delicate rebalanced hemostatic status of liver transplant recipients may lead to both hemorrhagic and thrombotic tendencies in this population. The aim of this study was to investigate the association between pretransplant procoagulants/anticoagulants and posttransplant bleeding and thrombosis among living donor liver transplant recipients.

Impact of multiple transarterial chemoembolization treatments on hepatocellular carcinoma for patients awaiting liver transplantation

Eleonora Terzi, W. Ray Kim, William Sanchez, Michael R. Charlton, Paul Schmeltzer, Gregory J. Gores, James C. Andrews, Thomas C. Smyrk, Julie K. Heimbach – 5 November 2014 – Transarterial chemoembolization (TACE) is a common treatment for patients with hepatocellular carcinoma (HCC) who are awaiting liver transplantation (LT). The aim of this study was to assess the impact of multiple TACE treatments on tumor necrosis, tumor recurrence, and survival in these patients.

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