Portal myofibroblasts promote vascular remodeling underlying cirrhosis formation through the release of microparticles
Sara Lemoinne, Axelle Cadoret, Pierre‐Emmanuel Rautou, Haquima El Mourabit, Vlad Ratziu, Christophe Corpechot, Colette Rey, Nelly Bosselut, Véronique Barbu, Dominique Wendum, Gérard Feldmann, Chantal Boulanger, Corneliu Henegar, Chantal Housset, Dominique Thabut – 12 July 2014 – Liver fibrosis expanding from portal tracts and vascular remodeling are determinant factors in the progression of liver diseases to cirrhosis. In the present study, we examined the potential contribution of portal myofibroblasts (PMFs) to the vascular changes leading to cirrhosis.