Jane P. Messina, Isla Humphreys, Abraham Flaxman, Anthony Brown, Graham S. Cooke, Oliver G. Pybus, Eleanor Barnes – 28 July 2014 – Hepatitis C virus (HCV) exhibits high genetic diversity, characterized by regional variations in genotype prevalence. This poses a challenge to the improved development of vaccines and pan‐genotypic treatments, which require the consideration of global trends in HCV genotype prevalence. Here we provide the first comprehensive survey of these trends.

Elisabeth Lang, Sergios Gatidis, Noemi F. Freise, Hans Bock, Ralf Kubitz, Christian Lauermann, Hans Martin Orth, Caroline Klindt, Maximilian Schuier, Verena Keitel, Maria Reich, Guilai Liu, Sebastian Schmidt, Haifeng C. Xu, Syed M. Qadri, Diran Herebian, Aleksandra A. Pandyra, Ertan Mayatepek, Erich Gulbins, Florian Lang, Dieter Häussinger, Karl S. Lang, Michael Föller, Philipp A.

Ekihiro Seki, Robert F. Schwabe – 26 July 2014 – Inflammation is one of the most characteristic features of chronic liver disease of viral, alcoholic, fatty, and autoimmune origin. Inflammation is typically present in all disease stages and associated with the development of fibrosis, cirrhosis, and hepatocellular carcinoma. In the past decade, numerous studies have contributed to improved understanding of the links between hepatic inflammation and fibrosis.

Luke W. Meredith, Michelle J. Farquhar, Alexander W. Tarr, Jane A. McKeating – 26 July 2014

Laurence Preisser, Charline Miot, Hélène Guillou‐Guillemette, Elodie Beaumont, Etienne D Foucher, Erwan Garo, Simon Blanchard, Isabelle Frémaux, Anne Croué, Isabelle Fouchard, Françoise Lunel‐Fabiani, Jérôme Boursier, Philippe Roingeard, Paul Calès, Yves Delneste, Pascale Jeannin – 26 July 2014 – Chronic hepatitis C virus (HCV) infection is characterized by progressive hepatic fibrosis, a process dependent on monocyte recruitment and accumulation into the liver.

Ekihiro Seki, Robert F. Schwabe – 26 July 2014 – Inflammation is one of the most characteristic features of chronic liver disease of viral, alcoholic, fatty, and autoimmune origin. Inflammation is typically present in all disease stages and associated with the development of fibrosis, cirrhosis, and hepatocellular carcinoma. In the past decade, numerous studies have contributed to improved understanding of the links between hepatic inflammation and fibrosis.

George Michalopolous – 26 July 2014

Ju Dong Yang, Cynthia D. Guy, Ayako Suzuki – 26 July 2014

Anatoliy I. Masyuk, Sergio A. Gradilone, Nicholas F. LaRusso – 26 July 2014

Cédric Coulouarn – 26 July 2014