Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation

Yuhei Hamaguchi, Toshimi Kaido, Shinya Okumura, Yasuhiro Fujimoto, Kohei Ogawa, Akira Mori, Ahmed Hammad, Yumiko Tamai, Nobuya Inagaki, Shinji Uemoto – 1 August 2014 – Intramuscular fat accumulation has come to be associated with loss of muscle strength and function, one of the components of sarcopenia. However, the impact of preoperative quality of skeletal muscle on outcomes after living donor liver transplantation (LDLT) is unclear.

Plasma protein biomarkers enhance the clinical prediction of kidney injury recovery in patients undergoing liver transplantation

Josh Levitsky, Talia B. Baker, Chunfa Jie, Shubhada Ahya, Murray Levin, John Friedewald, Patrice Al‐Saden, Daniel R. Salomon, Michael M. Abecassis – 31 July 2014 – Biomarkers predictive of recovery from acute kidney injury (AKI) after liver transplantation (LT) could enhance decision algorithms regarding the need for liver‐kidney transplantation or renal sparing regimens. Multianalyte plasma/urine kidney injury protein panels were performed immediately before and 1 month post‐LT in an initial test group divided by reversible pre‐LT AKI (rAKI = post‐LT renal recovery) versus no AKI (nAKI).

Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus

Franziska S. Hoffmann, Andreas Schmidt, Meike Dittmann Chevillotte, Christian Wisskirchen, Johannes Hellmuth, Simone Willms, Rachel H. Gilmore, Jürgen Glas, Matthias Folwaczny, Tobias Müller, Thomas Berg, Ulrich Spengler, Karen Fitzmaurice, Dermot Kelleher, Nicole Reisch, Charles M. Rice, Stefan Endres, Simon Rothenfusser – 30 July 2014

Clinical outcomes of hepatitis B virus coinfection in a United States cohort of hepatitis C virus‐infected patients

Robert L. Kruse, Jennifer R. Kramer, Gia L. Tyson, Zhigang Duan, Liang Chen, Hashem B. El‐Serag, Fasiha Kanwal – 28 July 2014 – The effect of hepatitis B virus (HBV) coinfection in patients with hepatitis C virus (HCV) remains unclear. We used the National Veterans Affairs HCV Clinical Case Registry to identify patients with confirmed HCV viremia during 1997‐2005. We defined HBV coinfection as a positive test for hepatitis B surface antigen, HBV DNA, or hepatitis B e antigen.

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