Understanding the pathophysiological regulatory role of microRNAs in acute liver failure
Daniel J. Antoine, James W. Dear, Christopher E. Goldring, B. Kevin Park – 1 August 2014
Mouse hepatocyte overexpression of NF‐κB‐inducing kinase (NIK) triggers fatal macrophage‐dependent liver injury and fibrosis
Hong Shen, Liang Sheng, Zheng Chen, Lin Jiang, Haoran Su, Lei Yin, M. Bishr Omary, Liangyou Rui – 1 August 2014
Inflammation‐based scores do not predict post‐transplant recurrence of hepatocellular carcinoma in patients within milan criteria
Ioanna Parisi, Emmanuel Tsochatzis, Hasitha Wijewantha, Manuel Rodríguez‐Perálvarez, Laura De Luca, Pinelopi Manousou, Evangelia Fatourou, Giulia Pieri, Vassilios Papastergiou, Neil Davies, Dominic Yu, TuVinh Luong, Amar Paul Dhillon, Douglas Thorburn, David Patch, James O'Beirne, Tim Meyer, Andrew K. Burroughs – 1 August 2014 – Increased preoperative inflammation scores, such as neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR) and inflammation‐based index (IBI) have been related to post‐transplant HCC recurrence.
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Heike Bantel, Thomas Thum, Klaus Schulze‐Osthoff – 1 August 2014
Mutational landscape of hepatoblastoma goes beyond the Wnt‐β‐catenin pathway
Ze‐Guang Han – 31 July 2014
Does the interferon‐lambda rather than the interferon‐alpha pathway determine the outcome of hepatitis C virus infection?
Sabine Mihm, Ulrich Spengler, Ahmad Amanzada, Giuliano Ramadori – 31 July 2014
Plasma protein biomarkers enhance the clinical prediction of kidney injury recovery in patients undergoing liver transplantation
Josh Levitsky, Talia B. Baker, Chunfa Jie, Shubhada Ahya, Murray Levin, John Friedewald, Patrice Al‐Saden, Daniel R. Salomon, Michael M. Abecassis – 31 July 2014 – Biomarkers predictive of recovery from acute kidney injury (AKI) after liver transplantation (LT) could enhance decision algorithms regarding the need for liver‐kidney transplantation or renal sparing regimens. Multianalyte plasma/urine kidney injury protein panels were performed immediately before and 1 month post‐LT in an initial test group divided by reversible pre‐LT AKI (rAKI = post‐LT renal recovery) versus no AKI (nAKI).
Polymorphisms in melanoma differentiation‐associated gene 5 link protein function to clearance of hepatitis C virus
Franziska S. Hoffmann, Andreas Schmidt, Meike Dittmann Chevillotte, Christian Wisskirchen, Johannes Hellmuth, Simone Willms, Rachel H. Gilmore, Jürgen Glas, Matthias Folwaczny, Tobias Müller, Thomas Berg, Ulrich Spengler, Karen Fitzmaurice, Dermot Kelleher, Nicole Reisch, Charles M. Rice, Stefan Endres, Simon Rothenfusser – 30 July 2014
Conjugated bilirubin triggers anemia by inducing erythrocyte death
Elisabeth Lang, Sergios Gatidis, Noemi F. Freise, Hans Bock, Ralf Kubitz, Christian Lauermann, Hans Martin Orth, Caroline Klindt, Maximilian Schuier, Verena Keitel, Maria Reich, Guilai Liu, Sebastian Schmidt, Haifeng C. Xu, Syed M. Qadri, Diran Herebian, Aleksandra A. Pandyra, Ertan Mayatepek, Erich Gulbins, Florian Lang, Dieter Häussinger, Karl S. Lang, Michael Föller, Philipp A.
Global distribution and prevalence of hepatitis C virus genotypes
Jane P. Messina, Isla Humphreys, Abraham Flaxman, Anthony Brown, Graham S. Cooke, Oliver G. Pybus, Eleanor Barnes – 28 July 2014 – Hepatitis C virus (HCV) exhibits high genetic diversity, characterized by regional variations in genotype prevalence. This poses a challenge to the improved development of vaccines and pan‐genotypic treatments, which require the consideration of global trends in HCV genotype prevalence. Here we provide the first comprehensive survey of these trends.