Oncofetal long noncoding RNA PVT1 promotes proliferation and stem cell‐like property of hepatocellular carcinoma cells by stabilizing NOP2
Fang Wang, Ji‐Hang Yuan, Shao‐Bing Wang, Fu Yang, Sheng‐Xian Yuan, Chen Ye, Ning Yang, Wei‐Ping Zhou, Wen‐Lin Li, Wen Li, Shu‐Han Sun – 12 July 2014 – Many protein‐coding oncofetal genes are highly expressed in murine and human fetal liver and silenced in adult liver. The protein products of these hepatic oncofetal genes have been used as clinical markers for the recurrence of hepatocellular carcinoma (HCC) and as therapeutic targets for HCC. Herein we examined the expression profiles of long noncoding RNAs (lncRNAs) found in fetal and adult liver in mice.