Hepatitis E virus seroprevalence in the United States: No easy answers
Mark H. Kuniholm, Ronald E. Engle, Robert H. Purcell, Kenrad E. Nelson – 4 July 2014
Excess mortality on the liver transplant waiting list: Unintended policy consequences and model for End‐Stage Liver Disease (MELD) inflation
Patrick Grant Northup, Nicolas Michael Intagliata, Neeral Lalit Shah, Shawn Joseph Pelletier, Carl Lansing Berg, Curtis Kent Argo – 4 July 2014 – The Model for End‐Stage Liver Disease (MELD) allocation system for liver transplantation provides “exceptions” for diseases such as hepatocellular carcinoma (HCC). It was the aim of this study to assess equipoise between exception candidates and nonexception candidates on the waiting list and to assess if the exception system contributes to steadily increasing regional MELD at transplant.
Neural cell adhesion molecule and polysialic acid in ductular reaction: The puzzle is far from completed, but the picture is becoming more clear
Mario Strazzabosco, Luca Fabris – 4 July 2014
Hepatitis E virus seroprevalence in the National Health and Nutrition Examination Survey: Facts trump opinion
Ronald E. Engle, Mark H. Kuniholm, Kenrad E. Nelson, Robert H. Purcell – 4 July 2014
Cost‐effectiveness of noninvasive liver fibrosis tests for treatment decisions in patients with chronic hepatitis C
Emmanuel A. Tsochatzis, Catriona Crossan, Louise Longworth, Kurinchi Gurusamy, Manolo Rodriguez‐Peralvarez, Konstantinos Mantzoukis, Julia O'Brien, Evangelos Thalassinos, Vassilios Papastergiou, Anna Noel‐Storr, Brian Davidson, Andrew K. Burroughs – 4 July 2014 – The cost‐effectiveness of noninvasive tests (NITs) as alternatives to liver biopsy is unknown. We compared the cost‐effectiveness of using NITs to inform treatment decisions in adult patients with chronic hepatitis C (CHC).
A career forged in iron
Lawrie W. Powell – 4 July 2014
Fructose leads to hepatic steatosis in zebrafish that is reversed by mechanistic target of rapamycin (mTOR) inhibition
Valerie Sapp, Leah Gaffney, Steven F. EauClaire, Randolph P. Matthews – 4 July 2014 – Nonalcoholic fatty liver disease (NAFLD), the accumulation of lipid within hepatocytes, is increasing in prevalence. Increasing fructose consumption correlates with this increased prevalence, and rodent studies directly support fructose leading to NAFLD. The mechanisms of NAFLD and in particular fructose‐induced lipid accumulation remain unclear, although there is evidence for a role for endoplasmic reticulum (ER) stress and oxidative stress.
Not all (bile acids) who wander are lost: The first report of a patient with an isolated NTCP defect
Saul J. Karpen, Paul A. Dawson – 4 July 2014
Fructose leads to hepatic steatosis in zebrafish that is reversed by mechanistic target of rapamycin (mTOR) inhibition
Valerie Sapp, Leah Gaffney, Steven F. EauClaire, Randolph P. Matthews – 4 July 2014 – Nonalcoholic fatty liver disease (NAFLD), the accumulation of lipid within hepatocytes, is increasing in prevalence. Increasing fructose consumption correlates with this increased prevalence, and rodent studies directly support fructose leading to NAFLD. The mechanisms of NAFLD and in particular fructose‐induced lipid accumulation remain unclear, although there is evidence for a role for endoplasmic reticulum (ER) stress and oxidative stress.