Ribavirin improves the IFN‐γ response of natural killer cells to IFN‐based therapy of hepatitis C virus infection
Jens M. Werner, Elisavet Serti, Xenia Chepa‐Lotrea, Jonathan Stoltzfus, Golo Ahlenstiel, Mazen Noureddin, Jordan J. Feld, T. Jake Liang, Yaron Rotman, Barbara Rehermann – 23 February 2014 – Ribavirin (RBV) is an important component of interferon (IFN)‐based and direct antiviral treatment regimens for hepatitis C virus (HCV) infection. Immunomodulation, in particular improvement of the host IFN response, has been proposed as RBV's mechanism of action.