NRF2, not always friendly but perhaps misunderstood
George K. Michalopoulos – 23 February 2014
Gd‐EOB‐DTPA‐enhanced magnetic resonance imaging and alpha‐fetoprotein predict prognosis of early‐stage hepatocellular carcinoma
Taro Yamashita, Azusa Kitao, Osamu Matsui, Takehiro Hayashi, Kouki Nio, Mitsumasa Kondo, Naoki Ohno, Tosiaki Miyati, Hikari Okada, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuni Nakanuma, Hiroyuki Takamura, Tetsuo Ohta, Yasunari Nakamoto, Masakazu Yamamoto, Tadatoshi Takayama, Shigeki Arii, XinWei Wang, Shuichi Kaneko – 23 February 2014 – The survival of patients with hepatocellular carcinoma (HCC) is often individually different even after surgery for early‐stage tumors.
Lessons learned from excess mortality associated with Klebsiella pneumoniae carbapenemase 2–producing k. pneumoniae in liver transplant recipients
Christoph Lübbert, Arne C. Rodloff, Sven Laudi, Philipp Simon, Thilo Busch, Joachim Mössner, Michael Bartels, Udo X. Kaisers – 22 February 2014
Liver transplantation in the management of porphyria
Ashwani K. Singal, Charles Parker, Christine Bowden, Manish Thapar, Lawrence Liu, Brendan M. McGuire – 22 February 2014 – Porphyrias are a group of eight metabolic disorders, each resulting from a mutation that affects an enzyme of the heme biosynthetic pathway. Porphyrias are classified as hepatic or erythropoietic, depending upon the site where the gene defect is predominantly expressed.
Carbapenem‐resistant Klebsiella pneumoniae colonization at liver transplantation: A management challenge
Maddalena Giannella, Maria Cristina Morelli, Francesco Cristini, Giorgio Ercolani, Matteo Cescon, Michele Bartoletti, Sara Tedeschi, Eddi Pasqualini, Russell E. Lewis, Antonio Daniele Pinna, Pierluigi Viale – 22 February 2014
Role of protein kinase C isoforms in bile formation and cholestasis
M. Sawkat Anwer – 22 February 2014 – Transhepatic solute transport provides the osmotic driving force for canalicular bile formation. Choleretic and cholestatic agents affect bile formation, in part, by altering plasma membrane localizations of transporters involved in bile formation. These short‐term dynamic changes in transporter location are highly regulated posttranslational events requiring various cellular signaling pathways.
Role of protein kinase C isoforms in bile formation and cholestasis
M. Sawkat Anwer – 22 February 2014 – Transhepatic solute transport provides the osmotic driving force for canalicular bile formation. Choleretic and cholestatic agents affect bile formation, in part, by altering plasma membrane localizations of transporters involved in bile formation. These short‐term dynamic changes in transporter location are highly regulated posttranslational events requiring various cellular signaling pathways.
Impact of donor warm ischemia time on outcomes after donation after cardiac death liver transplantation
David P. Foley – 22 February 2014
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury
Branden D. Tarlow, Milton J. Finegold, Markus Grompe – 22 February 2014 – Proliferating ducts, termed “oval cells,” have long been thought to be bipotential, that is, produce both biliary ducts and hepatocytes during chronic liver injury. The precursor to oval cells is considered to be a facultative liver stem cell (LSC). Recent lineage tracing experiments indicated that the LSC is SRY‐related HMG box transcription factor 9 postive (Sox9+) and can replace the bulk of hepatocyte mass in several settings.
Liver transplantation in the management of porphyria
Ashwani K. Singal, Charles Parker, Christine Bowden, Manish Thapar, Lawrence Liu, Brendan M. McGuire – 22 February 2014 – Porphyrias are a group of eight metabolic disorders, each resulting from a mutation that affects an enzyme of the heme biosynthetic pathway. Porphyrias are classified as hepatic or erythropoietic, depending upon the site where the gene defect is predominantly expressed.