Etiology and mortality of spontaneous bacterial peritonitis in liver transplant recipients: A cohort study

Cristina Pérez‐Cameo, Víctor Vargas, Lluís Castells, Itxarone Bilbao, Isabel Campos‐Varela, Joan Gavaldà, Albert Pahissa, Oscar Len – 10 April 2014 – Spontaneous bacterial peritonitis (SBP) in liver transplantation (LT) recipients who progress to cirrhosis has received little attention. We investigated the adequacy of empirical treatment with third‐generation cephalosporins for SBP in this population and the impact of transplantation on the evolution of the infection. We performed a cohort study with 138 SBP episodes: 19 in LT patients and 119 in non‐LT patients.

Thymic stromal lymphopoietin and interleukin‐4 mediate the pathogenesis of halothane‐induced liver injury in mice

William R. Proctor, Mala Chakraborty, Aaron M. Fullerton, Midhun C. Korrapati, Pauline M. Ryan, Kenrick Semple, Jeffrey C. Morrison, Julia D. Berkson, Lynette S. Chea, Qian Yang, Albert P. Li, Rosanne Spolski, Erin E. West, Yrina Rochman, Warren J. Leonard, Mohammed Bourdi, Lance R. Pohl – 10 April 2014 – Liver eosinophilia has been associated with incidences of drug‐induced liver injury (DILI) for more than 50 years, although its role in this disease has remained largely unknown.

Helicobacter pylori might contribute to nonalcoholic fatty liver disease–related cardiovascular events by releasing prothrombotic and proinflammatory factors

Jannis Kountouras, Stergios A. Polyzos, Christos Zavos, Georgia Deretzi, Constantinos Kountouras, Elizabeth Vardaka, Panagiotis Katsinelos, Elena Tsiaousi, Nikolaos Grigoriadis, Iordanis Romiopoulos, Dimitrios Tzilves, Evangelia Giartza‐Taxidou – 10 April 2014

Phosphorylation of ABCB4 impacts its function: Insights from disease‐causing mutations

Julien Gautherot, Danièle Delautier, Marie‐Anne Maubert, Tounsia Aït‐Slimane, Gérard Bolbach, Jean‐Louis Delaunay, Anne‐Marie Durand‐Schneider, Delphine Firrincieli, Véronique Barbu, Nicolas Chignard, Chantal Housset, Michèle Maurice, Thomas Falguières – 10 April 2014 – The ABCB4 transporter mediates phosphatidylcholine (PC) secretion at the canalicular membrane of hepatocytes and its genetic defects cause biliary diseases.

Index‐based dietary patterns and risk of incident hepatocellular carcinoma and mortality from chronic liver disease in a prospective study

Wen‐Qing Li, Yikyung Park, Katherine A. McGlynn, Albert R. Hollenbeck, Philip R. Taylor, Alisa M. Goldstein, Neal D. Freedman – 9 April 2014 – The role of diet in hepatocellular carcinoma (HCC) and its typical precursor, chronic liver disease (CLD), is poorly understood. Following dietary recommendations has been shown to reduce risk of many cancers, but whether such diets are associated with HCC and CLD is unknown.

Generation of functional cholangiocyte‐like cells from human pluripotent stem cells and HepaRG cells

Noushin Dianat, Hélène Dubois‐Pot‐Schneider, Clara Steichen, Christophe Desterke, Philippe Leclerc, Aurélien Raveux, Laurent Combettes, Anne Weber, Anne Corlu, Anne Dubart‐Kupperschmitt – 9 April 2014 – Cholangiocytes are biliary epithelial cells, which, like hepatocytes, originate from hepatoblasts during embryonic development.

Generation of functional cholangiocyte‐like cells from human pluripotent stem cells and HepaRG cells

Noushin Dianat, Hélène Dubois‐Pot‐Schneider, Clara Steichen, Christophe Desterke, Philippe Leclerc, Aurélien Raveux, Laurent Combettes, Anne Weber, Anne Corlu, Anne Dubart‐Kupperschmitt – 9 April 2014 – Cholangiocytes are biliary epithelial cells, which, like hepatocytes, originate from hepatoblasts during embryonic development.

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