Effect of the pretransplant serum sodium concentration on outcomes following liver transplantation

Michael D. Leise, Byung Cheol Yun, Joseph J. Larson, Joanne T. Benson, Ju Dong Yang, Terry M. Therneau, Charles B. Rosen, Julie K. Heimbach, Scott W. Biggins, W. Ray Kim – 25 February 2014 – Hyponatremia is associated with an increased risk of mortality on the liver transplantation (LT) waiting list. Although the incorporation of the serum sodium (Na) level into the Model for End‐Stage Liver Disease score may reduce wait‐list mortality, concerns remain about a potential association between pre‐LT hyponatremia and decreased post‐LT survival.

HCV genotype 3 is associated with an increased risk of cirrhosis and hepatocellular cancer in a national sample of U.S. Veterans with HCV

Fasiha Kanwal, Jennifer R. Kramer, Jawad Ilyas, Zhigang Duan, Hashem B. El‐Serag – 24 February 2014 – Data show that viral genotype 1 may increase the risk of cirrhosis and hepatocellular carcinoma (HCC) compared to genotype 2 in patients with chronic hepatitis C virus (HCV) infection. However, the effect of HCV genotype 3 on cirrhosis and HCC risk is uncertain. We identified patients with active HCV infection, confirmed by positive polymerase chain reaction (PCR) and a known HCV genotype, from the VA HCV Clinical Case Registry between 2000 and 2009.

Gd‐EOB‐DTPA‐enhanced magnetic resonance imaging and alpha‐fetoprotein predict prognosis of early‐stage hepatocellular carcinoma

Taro Yamashita, Azusa Kitao, Osamu Matsui, Takehiro Hayashi, Kouki Nio, Mitsumasa Kondo, Naoki Ohno, Tosiaki Miyati, Hikari Okada, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Yasuni Nakanuma, Hiroyuki Takamura, Tetsuo Ohta, Yasunari Nakamoto, Masakazu Yamamoto, Tadatoshi Takayama, Shigeki Arii, XinWei Wang, Shuichi Kaneko – 23 February 2014 – The survival of patients with hepatocellular carcinoma (HCC) is often individually different even after surgery for early‐stage tumors.

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