Derek A. Mann – 16 March 2014 – Epigenetics is a term that encompasses a variety of regulatory processes that are able to crosstalk in order to influence gene expression and cell phenotype in response to environmental cues. A deep understanding of epigenetics offers the potential for fresh insights into the basis for complex chronic diseases and improved diagnostic and prognostic tools.
Derek A. Mann – 16 March 2014 – Epigenetics is a term that encompasses a variety of regulatory processes that are able to crosstalk in order to influence gene expression and cell phenotype in response to environmental cues. A deep understanding of epigenetics offers the potential for fresh insights into the basis for complex chronic diseases and improved diagnostic and prognostic tools.
Sara Montagnese, Sami Schiff, Piero Amodio – 13 March 2014
Pan Zhao, Zhenman Wei, Wanshu Liu – 13 March 2014
James E. Everhart, Constance E. Ruhl – 13 March 2014
Rajeshwar Mookerjee, Gautam Mehta, Rajiv Jalan – 13 March 2014
Konstantin Kazankov, Francisco Barrera, Holger Jon Møller, Bo Martin Bibby, Hendrik Vilstrup, Jacob George, Henning Grønbæk – 13 March 2014 – Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C virus (HCV) and 203 patients with chronic hepatitis B virus (HBV) before antiviral treatment.
Len Verbeke, Jonel Trebicka, Wim Laleman – 13 March 2014
Shi Yin, Hua Wang, Adeline Bertola, Dechun Feng, Ming‐jiang Xu, Yan Wang, Bin Gao – 13 March 2014 – Invariant natural killer T (iNKT) cells are a major subset of lymphocytes found in the liver. These cells mediate various functions, including hepatic injury, fibrogenesis, and carcinogenesis. However, the function of iNKT cells in liver regeneration remains unclear. In the present study, partial hepatectomy (PHx) was used to study liver regeneration. α‐Galactosylceramide (α‐GalCer), a specific ligand for iNKT cells, was used to induce iNKT cell activation.
Michael J. Englesbe, Amit K. Mathur, Seth A. Waits, John C. Magee – 12 March 2014