Aldo J. Montano‐Loza, Judith Meza‐Junco, Vickie E. Baracos, Carla M. M. Prado, Mang Ma, Glenda Meeberg, Crystal Beaumont, Puneeta Tandon, Nina Esfandiari, Michael B. Sawyer, Norman Kneteman – 26 March 2014 – Muscle depletion or sarcopenia is associated with increased mortality in patients with cirrhosis; how it affects mortality after liver transplantation requires further study. In this study, we aimed to establish whether sarcopenia predicts increased morbidity or mortality after liver transplantation.

Linda G. Griffith, Alan Wells, Donna B. Stolz – 26 March 2014 – Interest in “engineering liver” arises from multiple communities: therapeutic replacement; mechanistic models of human processes; and drug safety and efficacy studies.

Linda G. Griffith, Alan Wells, Donna B. Stolz – 26 March 2014 – Interest in “engineering liver” arises from multiple communities: therapeutic replacement; mechanistic models of human processes; and drug safety and efficacy studies.

Wei‐Heng Xu, Hong‐Gang Hu, Yuan Tian, Shao‐Zhan Wang, Jie Li, Jian‐Zhong Li, Xing Deng, Hui Qian, Lei Qiu, Zhen‐Lin Hu, Qiu‐Ye Wu, Yi‐Feng Chai, Cheng Guo, Wei‐Fen Xie, Jun‐Ping Zhang – 26 March 2014 – Liver fibrosis and its endstage, cirrhosis, represent a major public health problem worldwide. Activation of hepatic stellate cells (HSCs) is a central event in hepatic fibrosis. However, the proteins that control HSC activation are incompletely understood.

Monika Sarkar, Norah A. Terrault – 26 March 2014

Ricardo Marcos, Carla Correia‐Gomes – 25 March 2014

Irene Locatelli, Salvatore Sutti, Aastha Jindal, Marco Vacchiano, Cristina Bozzola, Chris Reutelingsperger, Dennis Kusters, Stefania Bena, Maurizio Parola, Claudia Paternostro, Elisabetta Bugianesi, Simon McArthur, Emanuele Albano, Mauro Perretti – 25 March 2014 – Annexin A1 (AnxA1) is an effector of the resolution of inflammation and is highly effective in terminating acute inflammatory responses. However, its role in chronic settings is less investigated.

Erica F. Clayton, Saloni Malik, Alexander Bonnel, Yifei Mu, Kim Olthoff, Abraham Shaked, Peter L. Abt, Heather Peterman, K. Rajender Reddy, Shane Ottmann, Emma E. Furth, Matthew H. Levine – 25 March 2014 – Liver transplantation has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC) that falls within certain size and numerical criteria for patients with cirrhosis. Cirrhotomimetic (CMM) HCC is an uncommon growth pattern that infiltrates cirrhotic parenchyma, can become extensive in size, and can evade detection via radiological studies.

Takeo Toshima, Ken Shirabe, Takasuke Fukuhara, Toru Ikegami, Tomoharu Yoshizumi, Yuji Soejima, Tetsuo Ikeda, Shinji Okano, Yoshihiko Maehara – 25 March 2014 – Autophagy is a homeostatic mechanism that regulates protein and organelle turnover and uses the amino acids from degraded proteins to produce adenosine 5'‐triphosphate (ATP). We investigated the activity of autophagy‐associated pathways in liver regeneration after partial hepatectomy (PHx) in liver‐specific autophagy‐related gene 5 (Atg5) knockout (KO) mice.

Suk‐Won Suh, Jeong‐Moo Lee, Tae You, Young Rok Choi, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh – 25 March 2014 – A certain degree of graft congestion in living donor liver transplantation (LDLT) using a right liver graft may be inevitable because of the mismatch between the inflow and outflow structures of the liver. The subsequent inflammatory reaction and rapid regeneration of the graft have been suggested as causes of tumor recurrence. Therefore, we investigated the influence of graft congestion on hepatocellular carcinoma (HCC) recurrence after LDLT.