Aisling Considine, J. Michael Tredger, Michael Heneghan, Kosh Agarwal, Marianne Samyn, Nigel D. Heaton, John G. O'Grady, Varuna R. Aluvihare – 13 October 2014 – Clinical outcomes, dose changes, and dose‐equalized tacrolimus concentrations were examined sequentially in 129 liver transplantation (LT) recipients after successful conversion to once daily modified‐release tacrolimus either early (within 1 month) or late (>1 month) after LT. The data were compared with data for a group of 60 patients maintained on twice daily conventional‐release tacrolimus.

Ling Li, Florin M. Selaru – 12 October 2014

Xiuling Zhi, Ling Lin, Shaoxian Yang, Krithika Bhuvaneshwar, Hongkun Wang, Yuriy Gusev, Mi‐Hye Lee, Bhaskar Kallakury, Narayan Shivapurkar, Katherine Cahn, Xuefei Tian, John L. Marshall, Stephen W. Byers, Aiwu R. He – 12 October 2014 – βII‐Spectrin (SPTBN1) is an adapter protein for Smad3/Smad4 complex formation during transforming growth factor beta (TGF‐β) signal transduction. Forty percent of SPTBN1+/− mice spontaneously develop hepatocellular carcinoma (HCC), and most cases of human HCC have significant reductions in SPTBN1 expression.

Yohei Fujii, Yoshihito Uchida, Satoshi Mochida – 12 October 2014

Morris Sherman, Jordi Bruix – 12 October 2014

Yohei Fujii, Yoshihito Uchida, Satoshi Mochida – 12 October 2014

Manlio Vinciguerra – 12 October 2014

Qilin Gu, Zongbin Cui – 12 October 2014

Tetsuji Fujita – 12 October 2014

Constantine J. Karvellas, R. Todd Stravitz, Holly Battenhouse, William M. Lee, Michael L. Schilsky, for the US Acute Liver Failure Study Group – 11 October 2014 – The benefit of therapeutic hypothermia (TH) in acute liver failure (ALF) has not been previously demonstrated in a controlled fashion. This study sought to determine the impact of TH on 21‐day survival and complications in ALF patients at high risk for cerebral edema. This was a retrospective cohort study of ALF patients in the US Acute Liver Failure Study Group with grade III or IV hepatic encephalopathy.