Role of platelets in systemic tissue protection after remote ischemic preconditioning
Patrick Starlinger, Thomas Gruenberger – 26 March 2014
Hypercaloric diets with increased meal frequency, but not meal size, increase intrahepatic triglycerides: A randomized controlled trial
Karin E. Koopman, Matthan W.A. Caan, Aart J. Nederveen, Anouk Pels, Mariette T. Ackermans, Eric Fliers, Susanne E. Fleur, Mireille J. Serlie – 26 March 2014 – American children consume up to 27% of calories from high‐fat and high‐sugar snacks. Both sugar and fat consumption have been implicated as a cause of hepatic steatosis and obesity but the effect of meal pattern is largely understudied. We hypothesized that a high meal frequency, compared to consuming large meals, is detrimental in the accumulation of intrahepatic and abdominal fat.
Severe muscle depletion predicts postoperative length of stay but is not associated with survival after liver transplantation
Aldo J. Montano‐Loza, Judith Meza‐Junco, Vickie E. Baracos, Carla M. M. Prado, Mang Ma, Glenda Meeberg, Crystal Beaumont, Puneeta Tandon, Nina Esfandiari, Michael B. Sawyer, Norman Kneteman – 26 March 2014 – Muscle depletion or sarcopenia is associated with increased mortality in patients with cirrhosis; how it affects mortality after liver transplantation requires further study. In this study, we aimed to establish whether sarcopenia predicts increased morbidity or mortality after liver transplantation.
Engineering liver
Linda G. Griffith, Alan Wells, Donna B. Stolz – 26 March 2014 – Interest in “engineering liver” arises from multiple communities: therapeutic replacement; mechanistic models of human processes; and drug safety and efficacy studies.
Engineering liver
Linda G. Griffith, Alan Wells, Donna B. Stolz – 26 March 2014 – Interest in “engineering liver” arises from multiple communities: therapeutic replacement; mechanistic models of human processes; and drug safety and efficacy studies.
Bioactive compound reveals a novel function for ribosomal protein S5 in hepatic stellate cell activation and hepatic fibrosis
Wei‐Heng Xu, Hong‐Gang Hu, Yuan Tian, Shao‐Zhan Wang, Jie Li, Jian‐Zhong Li, Xing Deng, Hui Qian, Lei Qiu, Zhen‐Lin Hu, Qiu‐Ye Wu, Yi‐Feng Chai, Cheng Guo, Wei‐Fen Xie, Jun‐Ping Zhang – 26 March 2014 – Liver fibrosis and its endstage, cirrhosis, represent a major public health problem worldwide. Activation of hepatic stellate cells (HSCs) is a central event in hepatic fibrosis. However, the proteins that control HSC activation are incompletely understood.
Ending vertical transmission of hepatitis B: The third trimester intervention
Monika Sarkar, Norah A. Terrault – 26 March 2014
The innate immune system of the liver: May it explain the stronger viral clearance in female sex?
Ricardo Marcos, Carla Correia‐Gomes – 25 March 2014
Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice
Irene Locatelli, Salvatore Sutti, Aastha Jindal, Marco Vacchiano, Cristina Bozzola, Chris Reutelingsperger, Dennis Kusters, Stefania Bena, Maurizio Parola, Claudia Paternostro, Elisabetta Bugianesi, Simon McArthur, Emanuele Albano, Mauro Perretti – 25 March 2014 – Annexin A1 (AnxA1) is an effector of the resolution of inflammation and is highly effective in terminating acute inflammatory responses. However, its role in chronic settings is less investigated.
Liver transplantation and cirrhotomimetic hepatocellular carcinoma: Classification and outcomes
Erica F. Clayton, Saloni Malik, Alexander Bonnel, Yifei Mu, Kim Olthoff, Abraham Shaked, Peter L. Abt, Heather Peterman, K. Rajender Reddy, Shane Ottmann, Emma E. Furth, Matthew H. Levine – 25 March 2014 – Liver transplantation has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC) that falls within certain size and numerical criteria for patients with cirrhosis. Cirrhotomimetic (CMM) HCC is an uncommon growth pattern that infiltrates cirrhotic parenchyma, can become extensive in size, and can evade detection via radiological studies.