Srinivasan Dasarathy – 18 March 2014

Kheng Choon Lim, Vivian W. Wang, Fahad J. Siddiqui, Luming Shi, Edwin S.Y. Chan, Hong Choon Oh, Say Beng Tan, Pierce K.H. Chow – 18 March 2014 – Both liver resection (LR) and cadaveric liver transplantation (CLT) are potentially curative treatments for patients with hepatocellular carcinoma (HCC) within the Milan criteria and with adequate liver function. Adopting either as a first‐line therapy carries major cost and resource implications.

Anaïs Pujals, Giuliana Amaddeo, Claire Castain, Paulette Bioulac‐Sage, Philippe Compagnon, Jessica Zucman‐Rossi, Daniel Azoulay, Karen Leroy, Elie Serge Zafrani, Julien Calderaro – 17 March 2014

Mathieu Gauthé, Laurence Bozec, Pierre Bedossa – 17 March 2014 – Sinusoidal obstruction syndrome (SOS) is a potentially fatal liver injury that mainly occurs after myeloablative chemotherapy. We report two cases of SOS investigated by 18F‐fluorodeoxyglucose positron emission tomography/computed tomography and treated with defibrotide. (Hepatology 2014;60:1789–1791)

Mathieu Gauthé, Laurence Bozec, Pierre Bedossa – 17 March 2014 – Sinusoidal obstruction syndrome (SOS) is a potentially fatal liver injury that mainly occurs after myeloablative chemotherapy. We report two cases of SOS investigated by 18F‐fluorodeoxyglucose positron emission tomography/computed tomography and treated with defibrotide. (Hepatology 2014;60:1789–1791)

Veena L. Venkat, Sarangarajan Ranganathan, George V. Mazariegos, Qing Sun, Rakesh Sindhi – 17 March 2014 – There is little detailed clinical information on recurrent primary sclerosing cholangitis (rPSC) after liver transplantation in children. Our purpose was to describe the characteristics of children who had experienced rPSC after liver transplantation so that we could identify potential risk factors for recurrence.

Mitra K. Nadim, Wanwarat Annanthapanyasut, Lea Matsuoka, Kari Appachu, Mark Boyajian, Lingyun Ji, Ashraf Sedra, Yuri S. Genyk – 17 March 2014 – Liver transplantation (LT) for patients with renal dysfunction is frequently complicated by major fluid shifts, acidosis, and electrolyte and coagulation abnormalities. Continuous renal replacement therapy (CRRT) has been previously shown to ameliorate these problems. We describe the safety and clinical outcomes of intraoperative hemodialysis (IOHD) during LT for a group of patients with high Model for End‐Stage Liver Disease (MELD) scores.

Gao Feng, Chen Jing, Zeng Qian, Guan Jun, Huang Danni – 17 March 2014

Derek A. Mann – 16 March 2014 – Epigenetics is a term that encompasses a variety of regulatory processes that are able to crosstalk in order to influence gene expression and cell phenotype in response to environmental cues. A deep understanding of epigenetics offers the potential for fresh insights into the basis for complex chronic diseases and improved diagnostic and prognostic tools.

Derek A. Mann – 16 March 2014 – Epigenetics is a term that encompasses a variety of regulatory processes that are able to crosstalk in order to influence gene expression and cell phenotype in response to environmental cues. A deep understanding of epigenetics offers the potential for fresh insights into the basis for complex chronic diseases and improved diagnostic and prognostic tools.