Indications for liver transplant and AASLD guidelines
Manish Thapar, Herbert L. Bonkovsky – 18 April 2014
Manish Thapar, Herbert L. Bonkovsky – 18 April 2014
Hashem B. El‐Serag, Fasiha Kanwal – 18 April 2014
Sathish Kumar Natarajan, Sally A. Ingham, Ashley M. Mohr, Cody J. Wehrkamp, Anuttoma Ray, Sohini Roy, Sophie C. Cazanave, Mary Anne Phillippi, Justin L. Mott – 18 April 2014 – Recent studies have identified a cholestatic variant of nonalcoholic fatty liver disease (NAFLD) with portal inflammation and ductular reaction. Based on reports of biliary damage, as well as increased circulating free fatty acids (FFAs) in NAFLD, we hypothesized the involvement of cholangiocyte lipoapoptosis as a mechanism of cellular injury.
Harshal Shah, Walter C. Hellinger, Michael G. Heckman, Nancy Diehl, Jefree A. Shalev, Darrin L. Willingham, C. Burcin Taner, Dana K. Perry, Justin Nguyen – 18 April 2014 – Surgical site infections (SSIs) after liver transplantation (LT) are associated with an increased risk of graft loss and death. The incidence of SSIs after LT and their risk factors have been determined for first LT but not for second LT. The importance of reporting the incidence of SSIs risk‐stratified by first LT versus second LT is not known.
Olivier Seror, Jean‐Charles Nault, Pierre Nahon, Gisele N'Kontchou, Jean‐Claude Trinchet – 18 April 2014
Kenneth S. H. Chok, Tan To Cheung, Regina C. L. Lo, Ferdinand S. K. Chu, Simon H. Y. Tsang, Albert C. Y. Chan, William W. Sharr, James Y. Y. Fung, Wing Chiu Dai, See Ching Chan, Sheung Tat Fan, Chung Mau Lo – 18 April 2014 – The objective of this study was to investigate the outcomes of high‐intensity focused ultrasound (HIFU) ablation as a bridging therapy for patients with hepatocellular carcinoma (HCC) who had been wait‐listed for deceased donor liver transplantation (DDLT).
Looi Cheng Ee, Rebecca Joanne Hill, Kerrie Beale, Charlton Noble, Jonathan Fawcett, Geoffrey John Cleghorn – 18 April 2014 – Malnutrition is common in end‐stage liver disease, but a correction after transplantation is expected. Body cell mass (BCM) assessment using total body potassium (TBK) measurements is considered the gold standard for assessing nutritional status. The aim of this study was to examine the BCM and, therefore, nutritional status of long‐term survivors after childhood liver transplantation.
Xiulong Song, Alexander Vasilenko, Yuan Chen, Leila Valanejad, Ruchi Verma, Bingfang Yan, Ruitang Deng – 11 April 2014 – Bile salt export pump (BSEP) is responsible for biliary secretion of bile acids, a rate‐limiting step in the enterohepatic circulation of bile acids and transactivated by nuclear receptor farnesoid X receptor (FXR). Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent disorder among diseases unique to pregnancy and primarily occurs in the third trimester of pregnancy, with a hallmark of elevated serum bile acids.
Julien Gautherot, Danièle Delautier, Marie‐Anne Maubert, Tounsia Aït‐Slimane, Gérard Bolbach, Jean‐Louis Delaunay, Anne‐Marie Durand‐Schneider, Delphine Firrincieli, Véronique Barbu, Nicolas Chignard, Chantal Housset, Michèle Maurice, Thomas Falguières – 10 April 2014 – The ABCB4 transporter mediates phosphatidylcholine (PC) secretion at the canalicular membrane of hepatocytes and its genetic defects cause biliary diseases.
Jannis Kountouras, Stergios A. Polyzos, Christos Zavos, Georgia Deretzi, Constantinos Kountouras, Elizabeth Vardaka, Panagiotis Katsinelos, Elena Tsiaousi, Nikolaos Grigoriadis, Iordanis Romiopoulos, Dimitrios Tzilves, Evangelia Giartza‐Taxidou – 10 April 2014