Prediagnostic circulating vitamin D levels and risk of hepatocellular carcinoma in European populations: A nested case‐control study

Veronika Fedirko, Talita Duarte‐Salles, Christina Bamia, Antonia Trichopoulou, Krasimira Aleksandrova, Dimitrios Trichopoulos, Elisabeth Trepo, Anne Tjønneland, Anja Olsen, Kim Overvad, Marie‐Christine Boutron‐Ruault, Françoise Clavel‐Chapelon, Marina Kvaskoff, Tilman Kühn, Annie Lukanova, Heiner Boeing, Brian Buijsse, Eleni Klinaki, Chrysanthi Tsimakidi, Alessio Naccarati, Giovanna Tagliabue, Salvatore Panico, Rosario Tumino, Domenico Palli, H. Bas Bueno‐de‐Mesquita, Peter D. Siersema, Petra H.

The biliary epithelium gives rise to liver progenitor cells

Daniel Rodrigo‐Torres, Silvia Affò, Mar Coll, Oriol Morales‐Ibanez, Cristina Millán, Delia Blaya, Anna Alvarez‐Guaita, Carles Rentero, Juan José Lozano, Miguel Angel Maestro, Myriam Solar, Vicente Arroyo, Joan Caballería, Leo A. van Grunsven, Carlos Enrich, Pere Ginès, Ramon Bataller, Pau Sancho‐Bru – 20 February 2014 – Severe liver diseases are characterized by expansion of liver progenitor cells (LPC), which correlates with disease severity. However, the origin and role of LPC in liver physiology and in hepatic injury remains a contentious topic.

Survival in infection‐related acute‐on‐chronic liver failure is defined by extrahepatic organ failures

Jasmohan S. Bajaj, Jacqueline G. O'Leary, K. Rajender Reddy, Florence Wong, Scott W. Biggins, Heather Patton, Michael B. Fallon, Guadalupe Garcia‐Tsao, Benedict Maliakkal, Raza Malik, Ram M. Subramanian, Leroy R. Thacker, Patrick S. Kamath, the North American Consortium for the Study of End-stage Liver Disease (NACSELD) – 20 February 2014 – Infections worsen survival in cirrhosis; however, simple predictors of survival in infection‐related acute‐on‐chronic liver failure (I‐ACLF) derived from multicenter studies are required in order to improve prognostication and resource allocation.

Late hepatic artery thrombosis after pediatric liver transplantation: A cross‐sectional study of 34 patients

Jesper M. Kivelä, Silja Kosola, Teija Kalajoki‐Helmiö, Heikki Mäkisalo, Hannu Jalanko, Christer Holmberg, Mikko P. Pakarinen, Jouni Lauronen – 18 February 2014 – Hepatic artery thrombosis (HAT) after liver transplantation (LT) increases patient morbidity and mortality. Early HAT is considered to occur within the first month after LT, whereas late HAT occurs after the first month. Few studies have addressed late HAT after LT, especially in pediatric patients. Between 1987 and 2007, 99 patients (age < 18 years) underwent deceased donor LT.

Potential impacts of the Affordable Care Act on the clinical practice of hepatology

Jayant A. Talwalkar – 15 February 2014 – The Patient Protection and Affordable Care Act (ACA), along with the Health Care and Education Reconciliation Act, was signed into law and upheld by the Supreme Court earlier this year. The ACA contains a variety of reforms that, if implemented, will significantly affect current models of healthcare delivery for patients with acute and chronic hepatobiliary diseases.

Potential impacts of the Affordable Care Act on the clinical practice of hepatology

Jayant A. Talwalkar – 15 February 2014 – The Patient Protection and Affordable Care Act (ACA), along with the Health Care and Education Reconciliation Act, was signed into law and upheld by the Supreme Court earlier this year. The ACA contains a variety of reforms that, if implemented, will significantly affect current models of healthcare delivery for patients with acute and chronic hepatobiliary diseases.

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