Emmy Ludwig – 6 February 2014

Michael Vouche, Ali Habib, Thomas J. Ward, Edward Kim, Laura Kulik, Daniel Ganger, Mary Mulcahy, Talia Baker, Michael Abecassis, Kent T. Sato, Juan‐Carlos Caicedo, Jonathan Fryer, Ryan Hickey, Elias Hohlastos, Robert J. Lewandowski, Riad Salem – 6 February 2014 – Resection and radiofrequency ablation (RFA) are treatment options for hepatocellular carcinoma (HCC) <3 cm; there is interest in expanding the role of ablation to 3‐5 cm. RFA is considered high‐risk when the lesion is in close proximity to critical structures.

Michael Vouche, Ali Habib, Thomas J. Ward, Edward Kim, Laura Kulik, Daniel Ganger, Mary Mulcahy, Talia Baker, Michael Abecassis, Kent T. Sato, Juan‐Carlos Caicedo, Jonathan Fryer, Ryan Hickey, Elias Hohlastos, Robert J. Lewandowski, Riad Salem – 6 February 2014 – Resection and radiofrequency ablation (RFA) are treatment options for hepatocellular carcinoma (HCC) <3 cm; there is interest in expanding the role of ablation to 3‐5 cm. RFA is considered high‐risk when the lesion is in close proximity to critical structures.

Constance E. Ruhl, Andy Menke, Catherine C. Cowie, James E. Everhart – 5 February 2014 – An association of hepatitis C virus (HCV) infection with diabetes has been reported in many studies, but few have been population based and applied standard criteria for diabetes diagnosis. We examined this relationship using recent population‐based data from the U.S. National Health and Nutrition Examination Survey. Adult participants (15,128) in the 1999‐2010 surveys had data on diabetes status and serum HCV antibody (anti‐HCV) or HCV RNA.

David L. Wyles, Maribel Rodriguez‐Torres, Eric Lawitz, Mitchell L. Shiffman, Stanislas Pol, Robert W. Herring, Benedetta Massetto, Bittoo Kanwar, James D. Trenkle, Phil S. Pang, Yanni Zhu, Hongmei Mo, Diana M. Brainard, G. Mani Subramanian, John G. McHutchison, François Habersetzer, Mark S.

Steven Schenker – 5 February 2014

Claudio Puoti, Lia Bellis, Olga Mitidieri Costanza, Maria Giuseppa Elmo – 5 February 2014

Hiroyuki Koike, Yasuharu Ueno, Takako Naito, Tomoya Shiina, Susumu Nakata, Rie Ouchi, Yuta Obana, Keisuke Sekine, Yun‐Wen Zheng, Takanori Takebe, Kyo‐ichi Isono, Haruhiko Koseki, Hideki Taniguchi – 4 February 2014 – Polycomb‐group (PcG) proteins play crucial roles in self‐renewal of stem cells by suppressing a host of genes through histone modifications. Identification of the downstream genes of PcG proteins is essential for elucidation of the molecular mechanisms of stem cell self‐renewal. However, little is known about the PcG target genes in tissue stem cells.

Yin‐Chu Chien, Chyi‐Feng Jan, Chun‐Ju Chiang, Hsu‐Sung Kuo, San‐Lin You, Chien‐Jen Chen – 4 February 2014 – Hepatitis B immunization has been documented to prevent fulminant hepatic failure (FHF) and hepatocellular carcinoma (HCC) by historical comparison studies in Taiwan. This study aimed to assess long‐term risks and predictors of various liver diseases associated with incomplete immunization in 3.8 million vaccinees.

Ting Li, Ashley L. Eheim, Sabine Klein, Frank E. Uschner, Amber C. Smith, Elizabeth Brandon‐Warner, Sriparna Ghosh, Herbert L. Bonkovsky, Jonel Trebicka, Laura W. Schrum – 4 February 2014 – Hepatic stellate cell (HSC) transdifferentiation from a quiescent, adipocyte‐like cell to a highly secretory and contractile myofibroblast‐like phenotype contributes to negative pathological consequences, including fibrosis/cirrhosis with portal hypertension (PH). Antiadipogenic mechanisms have been shown to underlie activation of HSCs.