Characterization of european ancestry nonalcoholic fatty liver disease‐associated variants in individuals of african and hispanic descent

Nicholette D. Palmer, Solomon K. Musani, Laura M. Yerges‐Armstrong, Mary F. Feitosa, Lawrence F. Bielak, Ruben Hernaez, Bratati Kahali, J. Jeffrey Carr, Tamara B. Harris, Min A. Jhun, Sharon L.R. Kardia, Carl D. Langefeld, Thomas H. Mosley, Jill M. Norris, Albert V. Smith, Herman A. Taylor, Lynne E. Wagenknecht, Jiankang Liu, Ingrid B. Borecki, Patricia A. Peyser, Elizabeth K.

Patatin‐like phospholipase domain‐containing 3 I148M affects liver steatosis in patients with chronic hepatitis B

Mauro Viganò, Luca Valenti, Pietro Lampertico, Floriana Facchetti, Benedetta Maria Motta, Roberta D'Ambrosio, Solange Romagnoli, Paola Dongiovanni, Benedetta Donati, Silvia Fargion, Massimo Colombo – 8 April 2013 – Steatosis is a common histopathological feature of chronic hepatitis B (CHB) and has been associated with severity of liver disease.

α‐fetoprotein levels after interferon therapy and risk of hepatocarcinogenesis in chronic hepatitis C

Yasuhiro Asahina, Kaoru Tsuchiya, Takashi Nishimura, Masaru Muraoka, Yuichiro Suzuki, Nobuharu Tamaki, Yutaka Yasui, Takanori Hosokawa, Ken Ueda, Hiroyuki Nakanishi, Jun Itakura, Yuka Takahashi, Masayuki Kurosaki, Nobuyuki Enomoto, Mina Nakagawa, Sei Kakinuma, Mamoru Watanabe, Namiki Izumi – 8 April 2013 – The effects of interferon (IFN) treatment and the post‐IFN treatment α‐fetoprotein (AFP) levels on risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C (CHC) are unknown.

Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis

Janosch Katt, Dorothee Schwinge, Tanja Schoknecht, Alexander Quaas, Ingo Sobottka, Eike Burandt, Christoph Becker, Markus F. Neurath, Ansgar W. Lohse, Johannes Herkel, Christoph Schramm – 8 April 2013 – T helper (Th)17 cells are important for host defense against bacteria and fungi, but are also involved in the pathogenesis of autoimmune diseases. In primary sclerosing cholangitis (PSC), bile fluid is frequently colonized with pathogens and its strong association with inflammatory bowel disease suggests the contribution of pathogen responses to disease pathogenesis.

Homeostasis model assessment of insulin resistance does not seem to predict response to telaprevir in chronic hepatitis C in the REALIZE trial

Zobair Younossi, Francesco Negro, Lawrence Serfaty, Stanislas Pol, Moises Diago, Stefan Zeuzem, Pietro Andreone, Eric J. Lawitz, Stuart Roberts, Roberto Focaccia, Graham R. Foster, Andrzej Horban, Isabelle Lonjon‐Domanec, Bruce Coate, Ralph DeMasi, Gaston Picchio, James Witek – 4 April 2013 – Baseline homeostasis model assessment‐estimated insulin resistance (HOMA‐IR), a marker for insulin resistance, has been associated with poor virologic response to peginterferon alpha/ribavirin (PR) in chronic hepatitis C.

Subscribe to