Small steps toward a better treatment for chronic hepatitis C infection: mericitabine, pegylated interferon, and ribavirin in the PROPEL and JUMP‐C trials
Dawn M. Torres, Stephen A. Harrison – 4 April 2013
Homeostasis model assessment of insulin resistance does not seem to predict response to telaprevir in chronic hepatitis C in the REALIZE trial
Zobair Younossi, Francesco Negro, Lawrence Serfaty, Stanislas Pol, Moises Diago, Stefan Zeuzem, Pietro Andreone, Eric J. Lawitz, Stuart Roberts, Roberto Focaccia, Graham R. Foster, Andrzej Horban, Isabelle Lonjon‐Domanec, Bruce Coate, Ralph DeMasi, Gaston Picchio, James Witek – 4 April 2013 – Baseline homeostasis model assessment‐estimated insulin resistance (HOMA‐IR), a marker for insulin resistance, has been associated with poor virologic response to peginterferon alpha/ribavirin (PR) in chronic hepatitis C.
Now you see it, now you don't
Eileen Plotkin, David N. Assis, James L. Boyer – 4 April 2013
Now you see it, now you don't
Eileen Plotkin, David N. Assis, James L. Boyer – 4 April 2013
Vitamin D‐binding protein gene polymorphisms may contribute to the racial disparity in genotype 1 chronic hepatitis C treatment outcome
Steven J. Weintraub, Jaquelyn F. Fleckenstein, Tony N. Marion, Margaret A. Madey – 2 April 2013
Role of Toll‐Like Receptor 4 in Mediating Multiorgan Dysfunction in Mice With Acetaminophen Induced Acute Liver Failure
Naina Shah, Montserrat Montes de Oca, Maria Jover‐Cobos, Ken‐ichi Tanamoto, Masashi Muroi, Kei‐ichi Sugiyama, Nathan A. Davies, Rajeshwar P. Mookerjee, Dipok Kumar Dhar, Rajiv Jalan – 2 April 2013 – Strategies for the prevention of multiorgan dysfunction (MOD) in acetaminophen (APAP)‐induced acute liver failure (ALF) are an unmet need.
Clinical predictors of post–liver transplant new‐onset heart failure
Waqas Qureshi, Chetan Mittal, Umair Ahmad, Zaid Alirhayim, Syed Hassan, Sophia Qureshi, Fatima Khalid – 2 April 2013 – Objectives of this study were (1) to evaluate preoperative predictors of systolic and diastolic heart failure in patients undergoing liver transplantation (LT) and (2) to describe the prognostic implications of systolic and diastolic heart failure in these patients. The onset of heart failure after orthotopic LT remains poorly understood. Data were obtained for all LT recipients between January 2000 and December 2010.
Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas
Nicolas Poté, Theodore Alexandrov, Julie Le Faouder, Samira Laouirem, Thibaut Léger, Mouniya Mebarki, Jacques Belghiti, Jean‐Michel Camadro, Pierre Bedossa, Valérie Paradis – 2 April 2013 – Microvascular invasion (MiVI) is a major risk factor in postoperative tumor recurrence and mortality in hepatocellular carcinoma (HCC). Unfortunately, this histological feature is usually missed by liver biopsy because of limited sampling, and MiVI is commonly detected only after surgery and examination of the full resected specimen.
Reply:
Edmondo Falleti, Carlo Fabris, Pierluigi Toniutto – 2 April 2013
Pegylated interferon and ribavirin: a therapeutic option in patients who fail to respond to telaprevir‐based triple therapy?
Chia‐Yen Dai, Wan‐Long Chuang, Ming‐Lung Yu – 2 April 2013