Vitamin D nuclear receptor deficiency promotes cholestatic liver injury by disruption of biliary epithelial cell junctions in mice

Delphine Firrincieli, Silvia Zúñiga, Colette Rey, Dominique Wendum, Elisabeth Lasnier, Dominique Rainteau, Thomas Braescu, Thomas Falguières, Mathieu Boissan, Axelle Cadoret, Chantal Housset, Nicolas Chignard – 20 May 2013 – Alterations in apical junctional complexes (AJCs) have been reported in genetic or acquired biliary diseases. The vitamin D nuclear receptor (VDR), predominantly expressed in biliary epithelial cells in the liver, has been shown to regulate AJCs.

Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials

Mazen Noureddin, Jessica Lam, Michael R. Peterson, Michael Middleton, Gavin Hamilton, Thuy‐Anh Le, Ricki Bettencourt, Chris Changchien, David A. Brenner, Claude Sirlin, Rohit Loomba – 20 May 2013 – The magnetic resonance imaging–estimated proton density fat fraction (MRI‐PDFF) is a novel imaging‐based biomarker that allows fat mapping of the entire liver, whereas the magnetic resonance spectroscopy–measured proton density fat fraction (MRS‐PDFF) provides a biochemical measure of liver fat in small regions of interest.

Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials

Mazen Noureddin, Jessica Lam, Michael R. Peterson, Michael Middleton, Gavin Hamilton, Thuy‐Anh Le, Ricki Bettencourt, Chris Changchien, David A. Brenner, Claude Sirlin, Rohit Loomba – 20 May 2013 – The magnetic resonance imaging–estimated proton density fat fraction (MRI‐PDFF) is a novel imaging‐based biomarker that allows fat mapping of the entire liver, whereas the magnetic resonance spectroscopy–measured proton density fat fraction (MRS‐PDFF) provides a biochemical measure of liver fat in small regions of interest.

Reply

Elisabetta Bacchi, Carlo Negri, Giovanni Targher, Massimo Lanza, Federico Schena, Paolo Moghetti – 20 May 2013

Donor risk index for African American liver transplant recipients with hepatitis C virus

Nathan J. Shores, Jennifer L. Dodge, Sandy Feng, Norah A. Terrault – 20 May 2013 – African American (AA) liver transplant (LT) recipients with hepatitis C virus (HCV) have higher rates of graft loss than other racial/ethnic groups. The Donor Risk Index (DRI) predicts graft loss but is neither race‐ nor disease‐specific and may not be optimal for assessing donor risk for AA HCV‐positive LT recipients. We developed a DRI for AA with HCV with the goal of enhancing graft loss predictions. All U.S.

Subscribe to