Ignacio A. Echenique, Michael G. Ison – 22 March 2013 – Advances in surgical techniques, immunosuppressive medications, and robust infectious disease prophylaxis have resulted in liver transplantation becoming the treatment of choice for patients with end‐stage liver disease and unresectable hepatocellular carcinoma. Nonetheless, organ transplantation is not without risk. Unexpected donor‐derived disease transmission is a newly recognized risk that complicates approximately 0.2% of all organ transplants.

Matthew D. Hickey, David J. Quan, Peter V. Chin‐Hong, John P. Roberts – 22 March 2013 – Latent tuberculosis infection is an important problem for solid organ transplant recipients because of the frequency of its occurrence and its potential for reactivation. Because of the high mortality rate associated with active tuberculosis infections in transplant recipients, guidelines from the American Thoracic Society recommend treatment for latent tuberculosis in this population.

Neta Barashi, Ido D. Weiss, Ori Wald, Hanna Wald, Katia Beider, Michal Abraham, Shiri Klein, Daniel Goldenberg, Jonathan Axelrod, Eli Pikarsky, Rinat Abramovitch, Evelyne Zeira, Eithan Galun, Amnon Peled – 21 March 2013 – Human hepatocellular carcinoma (HCC) is an inflammation‐induced cancer, which is the third‐leading cause of cancer mortality worldwide. We investigated the role of the chemokine receptors, CCR5 and CCR1, in regulating inflammation and tumorigenesis in an inflammation‐induced HCC model in mice.

Frank Tacke, Hiroyuki Yoneyama – 20 March 2013

Joachim Lupberger, François H.T. Duong, Isabel Fofana, Laetitia Zona, Fei Xiao, Christine Thumann, Sarah C. Durand, Patrick Pessaux, Mirjam B. Zeisel, Markus H. Heim, Thomas F. Baumert – 20 March 2013 – Interferon‐alpha (IFN‐α) exhibits its antiviral activity through signal transducer and activator of transcription protein (STAT) signaling and the expression of IFN response genes (IRGs). Viral infection has been shown to result in activation of epidermal growth factor receptor (EGFR)—a host cell entry factor used by several viruses, including hepatitis C virus.

Manjeet Deshmukh, Yujin Hoshida – 20 March 2013

Eva Knüppel, Dominik Bettinger, Wulf Euringer, Robert Thimme, Martin Roessle, Hans Christian Spangenberg, Michael Schultheiss – 20 March 2013

Saumya Pandey – 20 March 2013

Ranjeeta Bahirwani, Burc Barin, Kim Olthoff, Peter Stock, Barbara Murphy, K. Rajender Reddy, for the Solid Organ Transplantation in HIV: Multi‐Site Study Investigators – 20 March 2013 – Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) are both associated with chronic kidney disease (CKD), a major complication after orthotopic liver transplantation (OLT). The aim of this study was to assess predictors of post‐OLT CKD in HIV/HCV‐coinfected recipients versus HIV‐infected recipients without HCV (HIV/non‐HCV recipients).

Riad Salem, Vincenzo Mazzaferro, Bruno Sangro – 19 March 2013