Current issues and future trends in surveillance for hepatocellular carcinoma
Robert S. Rahimi, Adam C. Yopp, Amit G. Singal – 23 January 2013 – Watch a video presentation of this article
Current issues and future trends in surveillance for hepatocellular carcinoma
Robert S. Rahimi, Adam C. Yopp, Amit G. Singal – 23 January 2013 – Watch a video presentation of this article
Radiological diagnosis of hepatocellular carcinoma
Mark W. Russo, Christoph Wald – 23 January 2013 – Watch a video presentation of this article
What primary care providers need to know about hepatocellular carcinoma
Parul Dureja Agarwal – 23 January 2013 – Watch a video presentation of this article
Hepatocyte caspase‐8 is an essential modulator of steatohepatitis in rodents
Maximilian Hatting, Gang Zhao, Fabienne Schumacher, Gernot Sellge, Malika Al Masaoudi, Nikolaus Gaβler, Mark Boekschoten, Michael Müller, Christian Liedtke, Francisco Javier Cubero, Christian Trautwein – 21 January 2013 – In human and murine models of nonalcoholic steatohepatitis (NASH), increased hepatocyte apoptosis is a critical mechanism contributing to inflammation and fibrogenesis. Caspase 8 (Casp8) is essential for death‐receptor‐mediated apoptosis activity and therefore its modulation might be critical for the pathogenesis of NASH.
Spleen stiffness: Toward a noninvasive portal sphygmomanometer?
Juan G. Abraldes, Enric Reverter, Annalisa Berzigotti – 21 January 2013
Hepatic reticuloendothelial system cell iron deposition is associated with increased apoptosis in nonalcoholic fatty liver disease
Bryan D. Maliken, James E. Nelson, Heather M. Klintworth, Mary Beauchamp, Matthew M. Yeh, Kris V. Kowdley – 16 January 2013 – The aim of this study was to examine the relationship between the presence of hepatic iron deposition, apoptosis, histologic features, and serum markers of oxidative stress (OS) and cell death in nonalcoholic fatty liver disease (NAFLD). Clinical, biochemical, metabolic, and independent histopathologic assessment was conducted in 83 unselected patients with biopsy‐proven NAFLD from a single center.
Decreased risk of liver cancer with thiazolidinediones therapy in patients with type 2 diabetes: Results from a meta‐analysis
Feng Wang, Shu‐Zhi Zhao, Ming‐Yue Zhang, Yan‐Lei Ma, Peng Zhang, Huan‐Long Qin – 16 January 2013
Soluble receptor for advanced glycation end products and risk of liver cancer
Kristin A. Moy, Li Jiao, Neal D. Freedman, Stephanie J. Weinstein, Rashmi Sinha, Jarmo Virtamo, Demetrius Albanes, Rachael Z. Stolzenberg‐Solomon – 16 January 2013 – Binding of advanced glycation end products (AGEs) to their receptor (RAGE) increases oxidative stress and inflammation and may be involved in liver injury and subsequent carcinogenesis. Soluble RAGE (sRAGE) may neutralize the effects mediated by the AGE/RAGE complex. Epidemiologic studies examining sRAGE or AGEs in association with liver cancer are lacking.
Plasma interferon‐gamma‐inducible protein‐10 (IP‐10) levels during acute hepatitis C virus infection
Jason Grebely, Jordan J. Feld, Tanya Applegate, Gail V. Matthews, Margaret Hellard, Alana Sherker, Kathy Petoumenos, Geng Zang, Ineke Shaw, Barbara Yeung, Jacob George, Suzy Teutsch, John M. Kaldor, Vera Cherepanov, Julie Bruneau, Naglaa H. Shoukry, Andrew R. Lloyd, Gregory J. Dore – 16 January 2013 – Systemic levels of interferon‐gamma‐inducible protein‐10 (IP‐10) are predictive of treatment‐induced clearance in chronic hepatitis C virus (HCV).