Chad Walesky, Genea Edwards, Prachi Borude, Sumedha Gunewardena, Maura O'Neil, Byunggil Yoo, Udayan Apte – 12 January 2013 – Hepatocyte nuclear factor 4 alpha (HNF4α), the master regulator of hepatocyte differentiation, has been recently shown to inhibit hepatocyte proliferation by way of unknown mechanisms. We investigated the mechanisms of HNF4α‐induced inhibition of hepatocyte proliferation using a novel tamoxifen (TAM)‐inducible, hepatocyte‐specific HNF4α knockdown mouse model.

Angelina Mouralidarane, Junpei Soeda, Clara Visconti‐Pugmire, Anne‐Maj Samuelsson, Joaquim Pombo, Xanthi Maragkoudaki, Adil Butt, Ruma Saraswati, Marco Novelli, Guiseppe Fusai, Lucilla Poston, Paul D. Taylor, Jude A. Oben – 12 January 2013 – The global prevalence of obesity‐induced liver disease (nonalcoholic fatty liver disease; NAFLD) is rising. Suggested causes include a role for in utero influences of maternal obesity compounded by the availability of energy‐dense foods throughout postnatal life.

Wolfgang Sieghart, Florian Hucke, Matthias Pinter, Ivo Graziadei, Wolfgang Vogel, Christian Müller, Harald Heinzl, Michael Trauner, Markus Peck‐Radosavljevic – 12 January 2013 – We aimed to establish an objective point score to guide the decision for retreatment with transarterial chemoembolization (TACE) in patients with hepatocellular carcinoma (HCC).

M. Eric Gershwin, Patrick S.C. Leung, William M. Ridgway, Ross L. Coppel, Aftab A. Ansari – 12 January 2013

Simon Hohenester, Ulrich Beuers, Juan F. Medina, Ronald P. Oude Elferink – 12 January 2013

David Fuks, Francois Durand, Jacques Belghiti – 12 January 2013

Xiao‐Yong Huang, Ai‐Wu Ke, Guo‐Ming Shi, Xin Zhang, Chi Zhang, Ying‐Hong Shi, Xiao‐Ying Wang, Zhen‐Bin Ding, Yong‐Sheng Xiao, Jun Yan, Shuang‐Jian Qiu, Jia Fan, Jian Zhou – 12 January 2013 – The overall survival of patients with hepatocellular carcinoma (HCC) remains poor, and the molecular pathogenesis remains incompletely defined in HCC. Here we report that increased expression of αB‐Crystallin in human HCC predicts poor survival and disease recurrence after surgery.

Sasan Roayaie, Josep Llovet, Myron Schwartz, Vincenzo Mazzaferro – 12 January 2013

Jean‐François Dufour – 12 January 2013

Wei Wei, Juan Hou, Olivia Alder, Xin Ye, Sam Lee, Rebecca Cullum, Andy Chu, Yongjun Zhao, Stephanie M. Warner, Darryl A. Knight, Decheng Yang, Steven J.M. Jones, Marco A. Marra, Pamela A. Hoodless – 12 January 2013 – MicroRNAs (miRNAs) are recently discovered small RNA molecules that regulate developmental processes, such as proliferation, differentiation, and apoptosis; however, the identity of miRNAs and their functions during liver development are largely unknown.