Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake

Gitte Dam, Susanne Keiding, Ole L. Munk, Peter Ott, Hendrik Vilstrup, Lasse K. Bak, Helle S. Waagepetersen, Arne Schousboe, Michael Sørensen – 10 August 2012 – Studies have shown decreased cerebral oxygen metabolism (CMRO2) and blood flow (CBF) in patients with cirrhosis with hepatic encephalopathy (HE). It remains unclear, however, whether these disturbances are associated with HE or with cirrhosis itself and how they may relate to arterial blood ammonia concentration and cerebral metabolic rate of blood ammonia (CMRA).

Predictors of early graft survival after pediatric liver transplantation

Ruben Ciria, Diego Davila, Shirin E. Khorsandi, Faisal Dar, Roberto Valente, Javier Briceño, Hector Vilca‐Melendez, Anil Dhawan, Mohamed Rela, Nigel D. Heaton – 10 August 2012 – The objective of this study was to identify peritransplant predictors of early graft survival and posttransplant parameters that could be used to predict early graft outcomes after pediatric liver transplantation (PLT). The response of children to liver dysfunction after liver transplantation (LT) is poor.

Intravenous N‐acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: A placebo‐controlled clinical trial

Robert H. Squires, Anil Dhawan, Estella Alonso, Michael R. Narkewicz, Benjamin L. Shneider, Norberto Rodriguez‐Baez, Dominic Dell Olio, Saul Karpen, John Bucuvalas, Steven Lobritto, Elizabeth Rand, Philip Rosenthal, Simon Horslen, Vicky Ng, Girish Subbarao, Nanda Kerkar, David Rudnick, M. James Lopez, Kathleen Schwarz, Rene Romero, Scott Elisofon, Edward Doo, Patricia R. Robuck, Sharon Lawlor, Steven H.

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