Xiao Qi Wang, Cindy K.Y. Cheung, Chung Mau Lo – 30 October 2012

Zhigang Tian, Yongyan Chen, Bin Gao – 30 October 2012 – Natural killer (NK) cells are enriched in lymphocytes within the liver and have unique phenotypic features and functional properties, including tumor necrosis factor–related apoptosis‐inducing ligand–‐dependent cytotoxicity and specific cytokine profiles.

Zhigang Tian, Yongyan Chen, Bin Gao – 30 October 2012 – Natural killer (NK) cells are enriched in lymphocytes within the liver and have unique phenotypic features and functional properties, including tumor necrosis factor–related apoptosis‐inducing ligand–‐dependent cytotoxicity and specific cytokine profiles.

Shmuel Shoham – 29 October 2012

Silja Kosola, Hanna Lampela, Hannu Jalanko, Heikki Mäkisalo, Jouko Lohi, Johanna Arola, Mikko P. Pakarinen – 29 October 2012 – Controversy remains about the role of protocol liver biopsy for symptom‐free recipients and about the long‐term use of low‐dose steroids after pediatric liver transplantation (LT). We conducted a national cross‐sectional study of pediatric recipients who underwent LT between 1987 and 2007.

Henrik Petrowsky, Fady Kaldas, Warwick Peacock, Dean Fisher, Johnny C. Hong, Charles Lassman, Ronald W. Busuttil – 19 October 2012

Jeffrey B. Halldorson, Harry J. Paarsch, Jennifer L. Dodge, Alberto M. Segre, Jennifer Lai, John Paul Roberts – 19 October 2012 – In the United States, livers for transplantation are distributed within donation service areas (DSAs). In DSAs with multiple transplant centers, competition among centers for organs and recipients may affect recipient selection and outcomes in comparison with DSAs with only 1 center. The objective of this study was to determine whether competition within a DSA is associated with posttransplant outcomes and variations in patients wait‐listed within the DSA.

Qiong‐Zhu Dong, Xiao‐Fei Zhang, Yue Zhao, Hu‐Liang Jia, Hai‐Jun Zhou, Chun Dai, Hai‐Jing Sun, Yi Qin, Wei‐De Zhang, Ning Ren, Qing‐Hai Ye, Lun‐Xiu Qin – 18 October 2012 – Osteopontin (OPN) plays a crucial role in hepatocellular carcinoma (HCC) metastasis. However, little is known about the impact of OPN polymorphisms on cancer progression. In this study, we first identified the single nucleotide polymorphisms (SNPs) in the OPN promoter region by direct sequencing in 30 HCCs, and then evaluated the prognostic values of the selected ones in two large cohorts of 826 HCC patients.

Ya‐Hui Chen, Mei‐Hwei Chang, Chin‐Sung Chien, Shang‐Hsin Wu, Chun‐Hsien Yu, Hui‐Ling Chen – 18 October 2012 – The potential lineage relationship between hepatic oval cells, small hepatocyte‐like progenitor cells (SHPCs), and hepatocytes in liver regeneration is debated. To test whether mature hepatocytes can give rise to SHPCs, rats with dipeptidyl peptidase IV (DPPIV) chimeric livers, which harbored endogenous DPPIV‐deficient hepatocytes and transplanted DPPIV‐positive hepatocytes, were subjected to retrorsine treatment followed by partial hepatectomy (PH).

Muhammad N. Zahid, Marine Turek, Fei Xiao, Viet Loan Dao Thi, Maryse Guérin, Isabel Fofana, Philippe Bachellier, John Thompson, Leen Delang, Johan Neyts, Dorothea Bankwitz, Thomas Pietschmann, Marlène Dreux, François‐Loïc Cosset, Fritz Grunert, Thomas F. Baumert, Mirjam B. Zeisel – 18 October 2012 – Scavenger receptor class B type I (SR‐BI) is a high‐density lipoprotein (HDL) receptor highly expressed in the liver and modulating HDL metabolism.