Glycogen synthase kinase 3‐mediated voltage‐dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation
Cecile Martel, Maya Allouche, Davide Degli Esposti, Elena Fanelli, Céline Boursier, Céline Henry, Joel Chopineau, Giuseppe Calamita, Guido Kroemer, Antoinette Lemoine, Catherine Brenner – 19 July 2012 – Nonalcoholic steatosis is a liver pathology characterized by fat accumulation and severe metabolic alterations involving early mitochondrial impairment and late hepatocyte cell death. However, mitochondrial dysfunction mechanisms remain elusive.