Liver vitamin D receptor, CYP2R1, and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with nonalcoholic steatohepatitis or hepatitis C virus

Ilaria Barchetta, Simone Carotti, Giancarlo Labbadia, Umberto Vespasiani Gentilucci, Andrea Onetti Muda, Francesco Angelico, Gianfranco Silecchia, Frida Leonetti, Antonio Fraioli, Antonio Picardi, Sergio Morini, Maria Gisella Cavallo – 30 June 2012 – Evidence suggests an association between low serum 25‐hydroxy‐vitamin D3 [25(OH)D3] levels and the presence and prognosis of liver disease. Vitamin D receptor (VDR) has been widely detected in the liver, but its expression in the course of liver disease has never been investigated.

Antimicrobial therapeutic determinants of outcomes from septic shock among patients with cirrhosis

Yaseen M. Arabi, Saqib I. Dara, Ziad Memish, Abdulmajeed Al Abdulkareem, Hani M. Tamim, Nehad Al‐Shirawi, Joseph E. Parrillo, Peter Dodek, Stephen Lapinsky, Daniel Feinstein, Gordon Wood, Sandra Dial, Sergio Zanotti, Anand Kumar, for the Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group – 30 June 2012 – It is unclear whether practice‐related aspects of antimicrobial therapy contribute to the high mortality from septic shock among patients with cirrhosis.

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