High rate of unemployment after liver transplantation: Analysis of the United Network for Organ Sharing database

Amina Huda, Robert Newcomer, Charlene Harrington, Mary G. Blegen, Emmet B. Keeffe – 11 August 2011 – The goal of liver transplantation (LT) is to maximize the length and quality of a patient's life and facilitate his or her return to full productivity. The aims of this study were (1) to use the United Network for Organ Sharing (UNOS) data set to determine the proportions of recipients who were employed and unemployed within 24 months after LT between 2002 and 2008 and (2) to examine the factors associated with a return to employment.

Surveillance of epstein‐barr virus loads in adult liver transplantation: Associations with age, sex, posttransplant times, and transplant indications

Kirsten Schaffer, Jaythoon Hassan, Anthony Staines, Suzie Coughlan, Paul Holder, Gráinne Tuite, Aiden P. McCormick, Oscar Traynor, William W. Hall, Jeff Connell – 11 August 2011 – Epstein‐Barr virus (EBV)–associated posttransplant lymphoproliferative disorder (PTLD) is a life‐threatening complication after adult orthotopic liver transplantation (AOLT).

Events in procurement as risk factors for ischemic cholangiopathy in liver transplantation using donation after cardiac death donors

C. Burcin Taner, Ilynn G. Bulatao, Darrin L. Willingham, Dana K. Perry, Lena Sibulesky, Surakit Pungpapong, Jaime Aranda‐Michel, Andrew P. Keaveny, David J. Kramer, Justin H. Nguyen – 11 August 2011 – The use of donation after cardiac death (DCD) liver grafts is controversial because of the overall increased rates of graft loss and morbidity, which are mostly related to the consequences of ischemic cholangiopathy (IC).

Effect of intermittent hepatic inflow occlusion with the Pringle maneuver during donor hepatectomy in adult living donor liver transplantation with right hemiliver grafts: A prospective, randomized controlled study

Jae Berm Park, Jae‐Won Joh, Sung‐Joo Kim, Choon‐Hyuck David Kwon, Jae Min Chun, Jong Man Kim, Ju Ik Moon, Suk‐Koo Lee – 11 August 2011 – To evaluate the effects of intermittent hepatic inflow occlusion (IHIO) during donor hepatectomy for living donor liver transplantation (LDLT) in recipients and donors, we performed a single‐center, open‐label, prospective, parallel, randomized controlled study. Adult donor‐recipient pairs undergoing LDLT with right hemiliver grafts were randomized into IHIO and control groups (1:1). In the IHIO group, IHIO was performed during donor hepatectomy.

A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart

Michele Miragoli, Siti H. Sheikh Abdul Kadir, Mary N. Sheppard, Nicoló Salvarani, Matilda Virta, Sarah Wells, Max J. Lab, Viacheslav O. Nikolaev, Alexey Moshkov, William M. Hague, Stephan Rohr, Catherine Williamson, Julia Gorelik – 1 August 2011 – Intrahepatic cholestasis of pregnancy may be complicated by fetal arrhythmia, fetal hypoxia, preterm labor, and, in severe cases, intrauterine death. The precise etiology of fetal death is not known. However, taurocholate has been demonstrated to cause arrhythmia and abnormal calcium dynamics in cardiomyocytes.

Urinary ethyl glucuronide as a novel screening tool in patients pre‐ and post–liver transplantation improves detection of alcohol consumption

Katharina Staufer, Hilke Andresen, Eik Vettorazzi, Niels Tobias, Bjoern Nashan, Martina Sterneck – 1 August 2011 – Optimal selection of liver transplant candidates and early detection of alcohol relapse after orthotopic liver transplantation (OLT) is necessary to improve long‐term outcomes. In this study, urinary ethyl glucuronide (uEtG) was prospectively evaluated as a novel screening tool for alcohol detection in the transplant setting. Overall, 141 liver transplant candidates and recipients, visiting the outpatient clinic for a total of 308 times, were included.

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