Meital Gal‐Tanamy, Larisa Bachmetov, Amiram Ravid, Ruth Koren, Arie Erman, Ran Tur‐Kaspa, Romy Zemel – 25 July 2011 – Vitamin D supplementation was reported to improve the probability of achieving a sustained virological response when combined with antiviral treatment against hepatitis C virus (HCV). Our aim was to determine the in vitro potential of vitamin D to inhibit HCV infectious virus production and explore the mechanism(s) of inhibition. Here we show that vitamin D3 remarkably inhibits HCV production in Huh7.5 hepatoma cells.

Yun‐Fan Liaw – 25 July 2011 – This clinically relevant review focuses on recent findings concerning hepatitis B surface antigen (HBsAg) quantitation in untreated patients and treated patients with chronic hepatitis B. Recent studies and emerging data have shown that both HBsAg and hepatitis B virus (HBV) DNA levels decline during the natural course of a chronic HBV infection; they are lowest in the inactive phase, which is also characterized by the highest HBsAg/HBV DNA ratio.

25 July 2011

Toshiyuki Morisawa, Takahisa Yoshikawa, Motoshige Nabeshima – 25 July 2011

Jennifer Gamble, Mathew Vadas, Geoffrey McCaughan – 25 July 2011

Jian‐Hong Fang, Hui‐Chao Zhou, Chunxian Zeng, Jine Yang, Yinglin Liu, Xiuzhi Huang, Jing‐Ping Zhang, Xin‐Yuan Guan, Shi‐Mei Zhuang – 25 July 2011 – Hepatocellular carcinoma (HCC) is a highly vascularized tumor with frequent intrahepatic metastasis. Active angiogenesis and metastasis are responsible for rapid recurrence and poor survival of HCC. We previously found that microRNA‐29b (miR‐29b) down‐regulation was significantly associated with poor recurrence‐free survival of HCC patients.

Christoph Roderburg, Christian Trautwein, Tom Luedde – 25 July 2011

Rohan Manohar, Junji Komori, Lynda Guzik, Donna B. Stolz, Uma R. Chandran, William A. LaFramboise, Eric Lagasse – 25 July 2011 – The identification of resident stem cells in the mouse gallbladder is, to date, unexplored. In addition, the relationship between adult gallbladder stem cells and intrahepatic bile duct (IHBD) cells is not well understood. The aim of this study was to isolate stem cells from an adult mouse gallbladder and determine whether they were unique, compared to IHBD cells.

Danielle Brandman, Andrea Pingitore, Jennifer C. Lai, John P. Roberts, Linda Ferrell, Nathan M. Bass, Norah A. Terrault – 18 July 2011 – Recurrent hepatitis C virus (HCV) is the most common cause of graft loss for HCV‐infected recipients of liver transplantation (LT). Diabetes mellitus (DM) has been associated with increased rates of fibrosis progression, but whether steatosis affects post‐LT outcomes independently of DM is unclear.

Fu Yang, Ling Zhang, Xi‐song Huo, Ji‐hang Yuan, Dan Xu, Sheng‐xian Yuan, Nan Zhu, Wei‐ping Zhou, Guang‐shun Yang, Yu‐zhao Wang, Jing‐li Shang, Chun‐fang Gao, Feng‐rui Zhang, Fang Wang, Shu‐han Sun – 18 July 2011 – In recent years, long noncoding RNAs (lncRNAs) have been shown to have critical regulatory roles in cancer biology. However, the contributions of lncRNAs to hepatitis B virus (HBV)‐related hepatocellular carcinoma (HCC) remain largely unknown.