Haeryoung Kim, Gi Hong Choi, Deuk Chae Na, Ei Young Ahn, Gwang Il Kim, Jae Eun Lee, Jai Young Cho, Jeong Eun Yoo, Jin Sub Choi, Young Nyun Park – 11 July 2011 – There is a recently proposed subtype of hepatocellular carcinoma (HCC) that is histologically similar to usual HCC, but characterized by the expression of “stemness”‐related markers. A large‐scale study on two different cohorts of HCCs was performed to investigate the clinicopathologic features and epithelial‐mesenchymal transition (EMT)‐related protein expression status of this subtype of HCCs.

Nicole T. do O, Dennis Eurich, Christian Trautwein, Peter Neuhaus, Ulf P. Neumann, Hermann E. Wasmuth – 11 July 2011

Gabriele Rockenbach, Alexandre JosÉ De Melo Neto, Nêmora Tregnago Barcellos, Fernando Herz Wolff – 11 July 2011

Yu Mei, Sundararajah Thevananther – 11 July 2011 – Endothelial nitric oxide synthase (eNOS) is a critical modulator of vascular tone and blood flow and plays major roles in liver physiology and pathophysiology. Nitric oxide (NO) is widely recognized as one of the key humoral factors important for the initiation of liver regeneration in response to partial hepatectomy. Liver regeneration in response to partial hepatectomy is dependent on the efficiency of growth factor‐mediated cell‐cycle progression.

Konstantinos Gkouvatsos, John Wagner, George Papanikolaou, Giada Sebastiani, Kostas Pantopoulos – 11 July 2011 – Mutations of the HFE2 gene are linked to juvenile hemochromatosis, a severe hereditary iron overload disease caused by chronic hyperabsorption of dietary iron. HFE2 encodes hemojuvelin (Hjv), a membrane‐associated bone morphogenetic protein (BMP) coreceptor that enhances expression of the liver‐derived iron regulatory hormone hepcidin. Hjv is primarily expressed in skeletal muscles and at lower levels in the heart and the liver.

Muriel Girard, Anne‐Sophie Jannot, MArianne Besnard, Anne‐Louise Leutenegger, Emmanuel Jacquemin, Stanislas Lyonnet, Alexandra Henrion‐Caude – 11 July 2011

Christoph Neumann‐Haefelin, Cesar Oniangue‐Ndza, Thomas Kuntzen, Julia Schmidt, Katja Nitschke, John Sidney, Célia Caillet‐Saguy, Marco Binder, Nadine Kersting, Michael W. Kemper, Karen A. Power, Susan Ingber, Laura L. Reyor, Kelsey Hills‐Evans, Arthur Y. Kim, Georg M. Lauer, Volker Lohmann, Alessandro Sette, Matthew R. Henn, Stéphane Bressanelli, Robert Thimme, Todd M. Allen – 11 July 2011 – Human leukocyte antigen B27 is associated with spontaneous viral clearance in hepatitis C virus (HCV) infection.

Shinji Tanaka, Kaoru Mogushi, Mahmut Yasen, Daisuke Ban, Norio Noguchi, Takumi Irie, Atsushi Kudo, Noriaki Nakamura, Hiroshi Tanaka, Masakazu Yamamoto, Norihiro Kokudo, Tadatoshi Takayama, Seiji Kawasaki, Michiie Sakamoto, Shigeki Arii – 11 July 2011 – The prediction of cancer recurrence holds the key to improvement of the postoperative prognosis of patients. In this study, the recurrence of early‐stage hepatocellular carcinoma (HCC) after curative hepatectomy was analyzed by the genome‐wide gene‐expression profiling on cancer tissue and the noncancerous liver tissue.

Marta A. Kowalik, Giovanna M. Ledda‐Columbano, Silvia Giordano, Amedeo Columbano – 11 July 2011

Andrew J. Muir, Fred F. Poordad, John G. McHutchison, Mitchell L. Shiffman, Thomas Berg, Peter Ferenci, E. Jenny Heathcote, Jean‐Michel Pawlotsky, Stefan Zeuzem, Henk W. Reesink, Geoffrey Dusheiko, Emily C. Martin, Shelley George, Robert S. Kauffman, Nathalie Adda – 11 July 2011 – Retreatment with peginterferon alpha and ribavirin (PR) offers a limited chance of sustained virologic response (SVR) in patients who did not achieve SVR with prior PR treatment.