Living donor hepatectomy: The importance of the residual liver volume

Trevor W. Reichman, Charbel Sandroussi, Solomon M. Azouz, Lesley Adcock, Mark S. Cattral, Ian D. McGilvray, Paul D. Greig, Anand Ghanekar, Markus Selzner, Gary Levy, David R. Grant – 17 August 2011 – Living liver donation is a successful treatment for patients with end‐stage liver disease. Most adults are provided with a right lobe graft to ensure a generous recipient liver volume. Some centers are re‐exploring the use of smaller left lobe grafts to potentially reduce the donor risk.

Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats

Lung‐Yi Lee, Takashi Kaizu, Hideyoshi Toyokawa, Matthew Zhang, Mark Ross, Donna B. Stolz, Chao Huang, Chandrashekhar Gandhi, David A. Geller, Noriko Murase – 17 August 2011 – Ischemia/reperfusion (I/R) injury in liver grafts, which is initiated by cold preservation and is augmented by reperfusion, is a major problem that complicates graft quality, posttransplant patient care, and outcomes of liver transplantation (LT). Kupffer cells (KCs) play important roles in I/R injury; however, little is known about their changes during cold preservation.

Ductular reactions in human liver: Diversity at the interface

Annette S. H. Gouw, Andrew D. Clouston, Neil D. Theise – 16 August 2011 – Interest in hepatic ductular reactions (DRs) has risen in recent years because of a greater appreciation of their potential roles in regeneration, fibrogenesis, and carcinogenesis. However, confusion exists because there is significant, but often unappreciated diversity at the tissue, cellular, and subcellular levels in DRs of different diseases and stages of disease.

Events in procurement as risk factors for ischemic cholangiopathy in liver transplantation using donation after cardiac death donors

C. Burcin Taner, Ilynn G. Bulatao, Darrin L. Willingham, Dana K. Perry, Lena Sibulesky, Surakit Pungpapong, Jaime Aranda‐Michel, Andrew P. Keaveny, David J. Kramer, Justin H. Nguyen – 11 August 2011 – The use of donation after cardiac death (DCD) liver grafts is controversial because of the overall increased rates of graft loss and morbidity, which are mostly related to the consequences of ischemic cholangiopathy (IC).

Surveillance of epstein‐barr virus loads in adult liver transplantation: Associations with age, sex, posttransplant times, and transplant indications

Kirsten Schaffer, Jaythoon Hassan, Anthony Staines, Suzie Coughlan, Paul Holder, Gráinne Tuite, Aiden P. McCormick, Oscar Traynor, William W. Hall, Jeff Connell – 11 August 2011 – Epstein‐Barr virus (EBV)–associated posttransplant lymphoproliferative disorder (PTLD) is a life‐threatening complication after adult orthotopic liver transplantation (AOLT).

High rate of unemployment after liver transplantation: Analysis of the United Network for Organ Sharing database

Amina Huda, Robert Newcomer, Charlene Harrington, Mary G. Blegen, Emmet B. Keeffe – 11 August 2011 – The goal of liver transplantation (LT) is to maximize the length and quality of a patient's life and facilitate his or her return to full productivity. The aims of this study were (1) to use the United Network for Organ Sharing (UNOS) data set to determine the proportions of recipients who were employed and unemployed within 24 months after LT between 2002 and 2008 and (2) to examine the factors associated with a return to employment.

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