Identification of microRNA‐181 by genome‐wide screening as a critical player in EpCAM–positive hepatic cancer stem cells
Junfang Ji, Taro Yamashita, Anuradha Budhu, Marshonna Forgues, Hu‐Liang Jia, Cuiling Li, Chuxia Deng, Elaine Wauthier, Lola M. Reid, Qing‐Hai Ye, Lun‐Xiu Qin, Wen Yang, Hong‐Yang Wang, Zhao‐You Tang, Carlo M. Croce, Xin Wei Wang – 29 July 2009 – MicroRNAs (miRNAs) are endogenous small noncoding RNAs that regulate gene expression with functional links to tumorigenesis. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, and it is heterogeneous in clinical outcomes and biological activities.