Hugo E. Vargas, Lois Krahn – 29 October 2008

Bo Feng, Shengming Wu, Sa Lv, Junjian Fang, Feng Liu, Yu Li, Yan Gao, Xianzhong Yan, Fangting Dong, Lai Wei – 29 October 2008 – Fulminant hepatic failure (FHF) is one of the most challenging gastrointestinal emergencies encountered in clinical practice. Early identification of patients with FHF who need liver transplantation is very important. To construct a prediction model for the early diagnosis and prognosis of FHF, we studied the dynamics of metabolic intermediates and metabolic profiles with a D‐galactosamine (GalN)/lipopolysaccharide (LPS)–treated BALB/c mouse model of FHF.

Jasmohan S. Bajaj, Kia Saeian, Muhammad Hafeezullah, Jose Franco, Andrea Thompson, Rebecca Anderson – 29 October 2008 – The prevention of recidivism in alcoholic liver disease is one of the aims of pretransplant psychological evaluation (PE). Failure to fully disclose the extent of alcohol use is evidence of ongoing alcoholism. Driving under the influence (DUI) represents objective evidence of alcohol abuse, but verifying DUIs through official records is not standard during PE.

Walid Faraj, Faisal Dar, Gabriele Marangoni, Adam Bartlett, Hector Vilca Melendez, Dino Hadzic, Anil Dhawan, Georgina Mieli‐Vergani, Mohamed Rela, Nigel Heaton – 29 October 2008 – From October 1993 to February 2007, 25 liver transplantations were performed for hepatoblastoma. Of these 25, 18 children received cadaveric grafts, and 7 received left lateral segments from living donors.

Joseph Ahn, Stanley M. Cohen – 29 October 2008 – In November 2007, a liver transplant recipient was confirmed to have human immunodeficiency virus (HIV) and hepatitis C (HCV) infection after the organ procurement agency notified our institution that the donor has been HIV and HCV positive. We reviewed medical records and the collected blood sample results for HIV and HCV testing. A 66 year old female with nonalcoholic steatohepatitis cirrhosis underwent liver transplantation. The donor was a male who had sex with men who received multiple blood transfusions during resuscitation.

Ed Day, David Best, Ruth Sweeting, Rebecca Russell, Kerry Webb, George Georgiou, James Neuberger – 29 October 2008 – Transplantation for alcoholic liver disease is becoming increasingly common, and with adequate screening, short‐ to medium‐term outcomes are very good. However, while conducting a prospective study of the outcome of liver transplantation in Birmingham, United Kingdom, we observed that a research diagnosis of alcohol abuse or dependence was made in a number of cases in which no reference to alcohol problems had been made by the referring agency.

Morris Sherman – 29 October 2008

Jacques Bernuau, Elisabeth Nicand, François Durand – 29 October 2008

Joos Heisterkamp, Hendrik A. Marsman, Hassan Eker, Herold J. Metselaar, Hugo W. Tilanus, Geert Kazemier – 29 October 2008 – A novel J‐shaped incision for liver transplantation was introduced in attempt to reduce the wound‐related complication rate while maintaining comparable access. Some 58 consecutive patients with the classic Mercedes incision were compared with the following 60 consecutive patients with a J‐shaped incision. Nine of 60 patients (15%) with a J‐shaped incision were converted to an extensive incision.

Giampaolo Bianchi, Giulio Marchesini, Rebecca Marzocchi, Antonio D. Pinna, Marco Zoli – 29 October 2008 – Excessive weight gain, hypertension, hyperlipidemia, and diabetes are frequently observed in patients having undergone liver transplantation (LTx). These alterations are probably multifactorial in origin, and cluster to generate a metabolic syndrome (MS), increasing the risk of cardiovascular events.