Acute kidney injury in cirrhosis

Guadalupe Garcia‐Tsao, Chirag R. Parikh, Antonella Viola – 24 November 2008 – Acute renal failure (ARF), recently renamed acute kidney injury (AKI), is a relatively frequent problem, occurring in approximately 20% of hospitalized patients with cirrhosis. Although serum creatinine may underestimate the degree of renal dysfunction in cirrhosis, measures to diagnose and treat AKI should be made in patients in whom serum creatinine rises abruptly by 0.3 mg/dL or more (≥26.4 μmol/L) or increases by 150% or more (1.5‐fold) from baseline.

Pathobiology of biliary epithelia and cholangiocarcinoma: Proceedings of the Henry M. and Lillian Stratton basic research single‐topic conference

Alphonse E. Sirica, Michael H. Nathanson, Gregory J. Gores, Nicholas F. LaRusso – 24 November 2008 – In June 2008, the American Association for the Study of Liver Diseases (AASLD) sponsored the Henry M. and Lillian Stratton Basic Research Single‐Topic Conference on the Pathobiology of Biliary Epithelia and Cholangiocarcinoma, which was held in Atlanta, GA. Attendees from 12 different countries participated in this conference, making it a truly international scientific event.

Immune reconstitution syndrome after voriconazole treatment for cryptococcal meningitis in a liver transplant recipient

Gonzalo Crespo, Carlos Cervera, Javier Michelena, Francesc Marco, Asunción Moreno, Miquel Navasa – 29 October 2008 – A new entity that comprises symptomatic worsening of an infectious or inflammatory process despite appropriate treatment was described a few years ago in human immunodeficiency virus–infected patients receiving highly active antiretroviral therapy. This entity was defined as immune reconstitution syndrome, and it is believed to result from an intense inflammatory reaction in patients with an appropriately treated infection who recover immunological status.

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