Frédéric Kesteloot, Alexis Desmoulière, Isabelle Leclercq, Marc Thiry, Jorge E. Arrese, Darwin J. Prockop, Charles M. Lapière, Betty V. Nusgens, Alain Colige – 29 October 2007 – ADAMTS2 belongs to the “ADAM metallopeptidase with thrombospondin type 1 motif” (ADAMTS) family. Its primary function is to process collagen type I, II, III, and V precursors into mature molecules by excising the aminopropeptide. This process allows the correct assembly of collagen molecules into fibrils and fibers, which confers to connective tissues their architectural structure and mechanical resistance.

François Durand, Jacques Belghiti, Valérie Paradis – 29 October 2007 – Patients with compensated cirrhosis (and low Model for End‐Stage Liver Disease score) should not undergo transplantation unless they have small hepatocellular carcinoma (HCC). Therefore, presence of HCC should be definitely ascertained before deciding on transplantation in this group of patients.

Claus Hellerbrand, Hermann E. Wasmuth – 29 October 2007

Jose Castellote – 29 October 2007

Lorri A. Morford, Christina Davis, Lin Jin, Aneta Dobierzewska, Martha L. Peterson, Brett T. Spear – 29 October 2007 – The Glypican 3 (Gpc3) gene is expressed abundantly in the fetal liver, is inactive in the normal adult liver, and is frequently reactivated in hepatocellular carcinoma (HCC). This reactivation in HCC has led to considerable interest in Gpc3 as a diagnostic tumor marker and its possible role in tumorigenesis. Despite this interest, the basis for Gpc3 regulation is poorly understood.

Nicholas A. Shackel, Geoffrey W. McCaughan – 29 October 2007

M. Susan Mandell, Tamara J. Stoner, Rebecca Barnett, Abraham Shaked, Mark Bellamy, Gianni Biancofiore, Claus Niemann, Ann Walia, Youri Vater, Zung V. Tran, Igal Kam – 29 October 2007 – Small single‐institutional studies performed prior to the introduction of organ allocation using the Model for End‐Stage Liver Disease (MELD) suggest that early airway extubation of liver transplant recipients is a safe practice. We designed a multicenter study to examine adverse events associated with early extubation in patients selected for liver transplantation using MELD score.

Karen L. Swanson – 29 October 2007

Anastasios Koulaouzidis, Elmuhtady Said, Anthia Gatopoulou, John Moschos – 29 October 2007

J. Judy Chang, Alexander J. V. Thompson, Kumar Visvanathan, Stephen J. Kent, Paul U. Cameron, Fiona Wightman, Paul Desmond, Stephen A. Locarnini, Sharon R. Lewin – 29 October 2007 – Hepatitis B virus (HBV)‐specific T cells play a key role in clearance of the virus and in the pathogenesis of liver disease. Peripheral blood (n = 25) and liver biopsies (n = 19) were collected from individuals with chronic untreated HBV infection.