Neoadjuvant therapies for hepatocellular carcinoma before liver transplantation: A critical appraisal
Patricia M. Lopez, Augusto Villanueva, Sasan Roayaie, Josep M. Llovet – 28 November 2006
Liver sinusoidal endothelial cells: Their unique role in immune tolerance
James D. Perkins – 28 November 2006
Highlights in Liver Transplantation
28 November 2006
Delivery of antioxidative enzyme genes protects against ischemia/reperfusion–induced liver injury in mice
Song‐Qing He, Yan‐Hong Zhang, Senthil K. Venugopal, Christopher W. Dicus, Richard V. Perez, Rajen Ramsamooj, Michael H. Nantz, Mark A. Zern, Jian Wu – 28 November 2006 – Hepatic ischemia/reperfusion (I/R) injury is characterized by the generation of reactive oxygen species (ROS), such as superoxide anions and hydrogen peroxide. The aim of this study is to investigate whether antioxidative gene delivery by our polylipid nanoparticles (PLNP) is an effective approach for prevention of the injury.
Physiological incompatibilities of porcine hepatocytes for clinical liver support
Harald Schrem, Moritz Kleine, Jürgen Borlak, Jürgen Klempnauer – 28 November 2006 – In fulminant hepatic failure, the use of bioartificial liver support (BAL) with porcine hepatocytes is the subject of a current and controversial debate.1 Specifically, the issue of cross‐species physiological incompatibilities has not been addressed so far. We therefore investigated the effects of species‐specific cytokines in single and cocultures on hepatocyte function. Hepatocyte cultures were isolated from human resection specimens and from Landrace pigs.
The incidence of nonadherence after organ transplant: Ensuring that our efforts at counting really count
Mary Amanda Dew, Andrea F. DiMartini – 28 November 2006
Accuracy of liver stiffness measurement for the diagnosis of cirrhosis in patients with chronic liver diseases
Nathalie Ganne‐Carrié, Marianne Ziol, Victor de Ledinghen, Catherine Douvin, Patrick Marcellin, Laurent Castera, Daniel Dhumeaux, Jean‐Claude Trinchet, Michel Beaugrand – 28 November 2006 – A proper diagnosis of cirrhosis is essential for the management of patients with chronic liver diseases. We assessed the accuracy of liver stiffness measurement by Fibroscan for the diagnosis of cirrhosis in 1,257 patients with chronic liver diseases of various causes enrolled in a prospective multicenter study as well as clarified causes of discrepancies between liver histology and Fibroscan.
Serum amyloid A has antiviral activity against hepatitis C virus by inhibiting virus entry in a cell culture system
Muriel Lavie, Cécile Voisset, Ngoc Vu‐Dac, Virginie Zurawski, Gilles Duverlie, Czeslaw Wychowski, Jean Dubuisson – 28 November 2006 – Serum amyloid A (SAA) is an acute phase protein produced by the liver. SAA concentration increases markedly in the serum following inflammation and infection. Large increases in SAA concentration during the acute phase response suggest that SAA has a beneficial role in host defense.
A tribute to two liver transplant colleagues
Georges Mantion – 28 November 2006
Acute liver failure induced by green tea extracts: Case report and review of the literature
Michele Molinari, Kymberly D.S. Watt, Thomas Kruszyna, Rebecca Nelson, Mark Walsh, Weei‐Yuan Huang, Bjorn Nashan, Kevork Peltekian – 28 November 2006 – In industrialized countries, over‐the‐counter dietary supplements have become popular in preventing and treating an expanding list of medical conditions. Although most commercially available supplements have not been rigorously tested for safety and efficacy, they have found an enlarging market because they are considered natural.