Prophylactic effect of tenofovir on viral reactivation in immunocompromised pregnant women living with hepatitis B virus
Le Zhang, Shaoying Yang, Yongfu Yu, Suli Wang, Yuetian Yu, Yi Jin, Aimin Zhao, Yimin Mao, Liangjing Lu – 19 May 2022 – The appropriate prophylaxis for hepatitis B virus reactivation (HBVr) during gestation for immunocompromised pregnant women has yet to be determined. The prophylactic efficacy and safety of tenofovir disoproxil fumarate (TDF) in hepatitis B surface antigen (HBsAg)–positive patients and the HBVr risk in hepatitis B core antibody (HBcAb)–positive patients during gestation were investigated.