Pediatric Liver Disorders
The goal of the Pediatric Special Interest Group is to promote liver-related issues that affect infants, children and adolescents. The Pediatric SIG supports AASLD missions through committee memberships, educational programming and networking with related academic societies.
Organoids and regenerative hepatology
Nidhi Jalan‐Sakrikar, Teresa Brevini, Robert C. Huebert, Fotios Sampaziotis – 20 May 2022 – The burden of liver diseases is increasing worldwide, with liver transplantation remaining the only treatment option for end‐stage liver disease. Regenerative medicine holds great potential as a therapeutic alternative, aiming to repair or replace damaged liver tissue with healthy functional cells. The properties of the cells used are critical for the efficacy of this approach.
Quaternary nanoparticles enable sustained release of bortezomib for hepatocellular carcinoma
Ling Li, Yicheng Zhang, Yang Zhou, Haijie Hu, Yizong Hu, Christos Georgiades, Hai‐Quan Mao, Florin M. Selaru – 20 May 2022
Setting up criteria for drug‐induced autoimmune‐like hepatitis through a systematic analysis of published reports
Einar S. Björnsson, Inmaculada Medina‐Caliz, Raul J. Andrade, M. Isabel Lucena – 20 May 2022 – Nitrofurantoin, minocycline, methyldopa and infliximab, have been found to induce autoimmune‐like hepatitis (DI‐AILH). Evidence for other drugs and herbal and dietary supplements (HDS) is unclear. The aims of the study were to establish criteria to define and review the published evidence of suspected DI‐AILH.
High time for common ground in the assessment of steatosis
Benjamin Philosophe, Russell Noel Wesson – 20 May 2022
Progressive cholestasis and associated sclerosing cholangitis are frequent complications of COVID‐19 in patients with chronic liver disease
Lukas Hartl, Katharina Haslinger, Martin Angerer, Georg Semmler, Mathias Schneeweiss‐Gleixner, Mathias Jachs, Benedikt Simbrunner, David Josef Maria Bauer, Ernst Eigenbauer, Robert Strassl, Monika Breuer, Oliver Kimberger, Daniel Laxar, Katharina Lampichler, Emina Halilbasic, Albert Friedrich Stättermayer, Ahmed Ba‐Ssalamah, Mattias Mandorfer, Bernhard Scheiner, Thomas Reiberger, Michael Trauner – 20 May 2022
Use of preprocurement biopsy in donation after circulatory death liver transplantation
Alexandra C. Bolognese, David P. Foley, Carrie J. Sparks, Adam K. Schneider, Anthony M. D'Alessandro, Nikole A. Neidlinger – 20 May 2022 – We perform routine preprocurement image‐guided percutaneous liver biopsies on potential donation after circulatory death (DCD) liver donors. The purpose of this study was to examine the impact of preprocurement liver biopsy on the use of livers from DCD donors.
Transplantation in Acute‐on‐Chronic Liver Failure: Feasibility and Futility
Alexander Queck, Nina Weiler, Jonel Trebicka – 19 May 2022
Posttransplant complications in the setting of acute‐on‐chronic liver failure and considerations regarding immunosuppression
M. Valerie Lin, Fredric D. Gordon – 19 May 2022