Model for end‐stage liver disease (MELD) exception for portopulmonary hypertension
Michael J. Krowka, Michael B. Fallon, David C. Mulligan, Robert G. Gish – 22 November 2006
Model for end‐stage liver disease (MELD) exception for familial amyloidotic polyneuropathy
Elizabeth Pomfret, Robert G. Gish, David Brandhagen – 22 November 2006
Model for end‐stage liver disease (MELD) exception for uncommon hepatic tumors
Jeffrey Punch, Robert G. Gish – 22 November 2006
Model for end‐stage liver disease (MELD) exception small‐for‐size syndrome
Patricia Sheiner, Jacques Belghiti, Robert G. Gish, Charles Miller – 22 November 2006
Model for end‐stage liver disease (MELD) exception for cholangiocarcinoma or biliary dysplasia
Gregory J. Gores, Robert G. Gish, Debra Sudan, Charles B. Rosen – 22 November 2006
Model for end‐stage liver disease (MELD) exception for cystic fibrosis
Simon Horslen, Stuart Sweet, Robert G. Gish, Ross Shepherd – 22 November 2006
Model for end‐stage liver disease (MELD) exception for hepatic encephalopathy
John Ham, Robert G. Gish, Kevin Mullen – 22 November 2006
Model for end‐stage liver disease (MELD) exception for unusual metabolic liver diseases
Sue McDiarmid, Robert G. Gish, Simon Horslen, George V. Mazariegos – 22 November 2006
Model for end‐stage liver disease (MELD) exception for primary hyperoxaluria
Simon Horslen, Robert G. Gish, Ruth McDonald – 22 November 2006
Human UDP‐glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver
Jocelyn Trottier, Mélanie Verreault, Susan Grepper, Didier Monté, Julie Bélanger, Jenny Kaeding, Patrick Caron, Ted T. Inaba, Olivier Barbier – 20 October 2006 – Chenodeoxycholic acid (CDCA) is a liver‐formed detergent and plays an important role in the control of cholesterol homeostasis. During cholestasis, toxic bile acids (BA) accumulate in hepatocytes causing damage and consequent impairment of their function. Glucuronidation, a conjugation reaction catalyzed by UDP‐glucuronosyltransferase (UGT) enzymes, is considered an important metabolic pathway for hepatic BA.