Manjushree Gautam, Rekha Cheruvattath, Vijayan Balan – 9 October 2006 – Recurrence of autoimmune liver disease in allografts has long been a topic of debate. We conducted a systematic review of the literature to examine the reported incidence of recurrence after liver transplantation of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH). The MEDLINE, EMBASE, and Cochrane electronic databases were used to identify articles.

Thomas Gerhardt, Uwe Pöge, Birgit Stoffel‐Wagner, Manuela Ahrendt, Martin Wolff, Ulrich Spengler, Holger Palmedo, Tilman Sauerbruch, Rainer P. Woitas – 9 October 2006 – Early detection of renal dysfunction in patients after orthotopic liver transplantation is important. Creatinine‐based equations to estimate glomerular filtration rate (GFR) were found to be less accurate in liver transplant recipients than in their original populations.

Kassiani Theodoraki, Nikolaos Arkadopoulos, George Fragulidis, Dionysios Voros, Konstantinos Karapanos, Maria Markatou, Georgia Kostopanagiotou, Vassilios Smyrniotis – 9 October 2006 – Hepatectomies performed under selective hepatic vascular exclusion are associated with a series of events culminating in ischemia/reperfusion injury, a state that shares common characteristics with situations known to result in global or regional hyperlactatemia.

Gero Puhl, Peter Olschewski, Wenzel Schöning, Gerhard Hunold, Hans‐Georg Liesaus, Robert Winkler, Ulf P. Neumann, Thomas E.O. Schubert, Volker Schmitz, Peter Neuhaus – 9 October 2006 – Adequate flushing for liver donation requires large fluid volumes delivered at a high flow. This can be achieved more effectively with crystalloid solutions than with colloid‐based solutions. This study examined the combination of initial histidine‐tryptophan‐ketoglutarate solution (HTK) graft flush and subsequent storage in University of Wisconsin solution (UW) to that of the single use of each solution.

Jérôme Dumortier, Mustapha Adham, Charles Ber, Catherine Boucaud, Yves Bouffard, Bertrand Delafosse, Pierre Sagnard, Olivier Boillot – 9 October 2006 – While the number of candidates for liver transplantation has increased in the recent years, the pool of cadaveric donor organs has remained constant and the waiting time progressively increases. These facts led us to start a program of adult‐to‐adult living‐donor liver transplantation in 1998. The aim of this study was to compare the outcome of all patients put on the waiting list since 1998.

Alberto Grassi, Chiara Quarneti, Matteo Ravaioli, Francesco Bianchini, Micaela Susca, Antonia D'Errico, Fabio Piscaglia, Maria Rosa Tamè, Pietro Andreone, GianLuca Grazi, Silvia Galli, Daniela Zauli, Antonio D. Pinna, Francesco B. Bianchi, Giorgio Ballardini – 9 October 2006 – The aim of this study was to evaluate how the immunohistochemical detection of liver hepatitis C virus (HCV) antigens (HCV‐Ag) could support the histologic diagnosis and influence the clinical management of post‐liver transplantation (LT) liver disease.

Suk Seo, Kalyani Maganti, Manjit Khehra, Rajendra Ramsamooj, Alexander Tsodikov, Christopher Bowlus, John McVicar, Mark Zern, Natalie Torok – 6 October 2006 – Hepatic steatosis is a recognized problem in patients after orthotopic liver transplant (OLT). However, de novo development of nonalcoholic fatty liver disease (NAFLD) has not been well described. The aim of this study was to determine the prevalence and predictors of de novo NAFLD after OLT. A retrospective analysis was performed on 68 OLT patients with donor liver biopsies and posttransplantation liver biopsies.

Yo‐ichi Takei, Takahisa Gono, Masahide Yazaki, Shu‐ichi Ikeda, Toshihiko Ikegami, Yasuhiko Hashikura, Shin‐ichi Miyagawa, Yoshinobu Hoshii – 6 October 2006 – Familial amyloid polyneuropathy (FAP) is a form of hereditary generalized amyloidosis. Liver tissue explanted from FAP patients has normal structure and function, except for the production of amyloidogenic variant transthyretin (TTR), and domino liver transplantation (DLT) using grafts from FAP patients was first performed in 1995.

Judy Wai Ping Yam, Frankie Chi Fat Ko, Chung‐Yiu Chan, Tai‐On Yau, Edmund Kwok Kwan Tung, Thomas Ho‐Yin Leung, Dong‐Yan Jin, Irene Oi‐Lin Ng – 27 September 2006 – Tensins are a new family of proteins that act as an important link among extracellular matrix, actin cytoskeleton, and signal transduction and have been implicated in human cancers. Tensin2 was initially identified in a search for new tensin family members that share extensive sequence homology with tensin1. Tensin2 was highly expressed in liver tissues.

Mitsuteru Kitade, Hitoshi Yoshiji, Hideyuki Kojima, Yasuhide Ikenaka, Ryuichi Noguchi, Kosuke Kaji, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Kiyoshi Asada, Masaharu Yamazaki, Tatsuhiro Tsujimoto, Takemi Akahane, Masahito Uemura, Hiroshi Fukui – 27 September 2006 – Nonalcoholic steatohepatitis (NASH) may cause fibrosis, cirrhosis, and hepatocellular carcinoma (HCC); however, the exact mechanism of disease progression is not fully understood. Angiogenesis has been shown to play an important role in the progression of chronic liver disease.