Patrick S. Kamath – 18 October 2006 – Key Concepts: 1Diagnosis of Budd‐Chiari syndrome can be made on the basis of radiological imaging alone without the need for liver biopsy.2Ultrasonography, computed tomography, and magnetic resonance imaging all show various degrees of occlusion of the hepatic veins and/or inferior vena cava. Hypertrophy of the caudate lobe may also be seen.3Computed tomographic and magnetic resonance imaging give a better idea of hepatic perfusion.

James R. Burton, Hugo R.

Richard B. Freeman – 18 October 2006 – Key Concepts: 1Liver transplantation offers excellent results for selected candidates with hepatocellular carcinoma (HCC).2Selection strategies have evolved but are mainly based on size and number of tumors, which are surrogates for vascular invasion.

Bachir Taouli, Glenn A.

Manjushree Gautam, Rekha Cheruvattath, Vijayan Balan – 9 October 2006 – Recurrence of autoimmune liver disease in allografts has long been a topic of debate. We conducted a systematic review of the literature to examine the reported incidence of recurrence after liver transplantation of primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and autoimmune hepatitis (AIH). The MEDLINE, EMBASE, and Cochrane electronic databases were used to identify articles.

Thomas Gerhardt, Uwe Pöge, Birgit Stoffel‐Wagner, Manuela Ahrendt, Martin Wolff, Ulrich Spengler, Holger Palmedo, Tilman Sauerbruch, Rainer P. Woitas – 9 October 2006 – Early detection of renal dysfunction in patients after orthotopic liver transplantation is important. Creatinine‐based equations to estimate glomerular filtration rate (GFR) were found to be less accurate in liver transplant recipients than in their original populations.

Kassiani Theodoraki, Nikolaos Arkadopoulos, George Fragulidis, Dionysios Voros, Konstantinos Karapanos, Maria Markatou, Georgia Kostopanagiotou, Vassilios Smyrniotis – 9 October 2006 – Hepatectomies performed under selective hepatic vascular exclusion are associated with a series of events culminating in ischemia/reperfusion injury, a state that shares common characteristics with situations known to result in global or regional hyperlactatemia.

Gero Puhl, Peter Olschewski, Wenzel Schöning, Gerhard Hunold, Hans‐Georg Liesaus, Robert Winkler, Ulf P. Neumann, Thomas E.O. Schubert, Volker Schmitz, Peter Neuhaus – 9 October 2006 – Adequate flushing for liver donation requires large fluid volumes delivered at a high flow. This can be achieved more effectively with crystalloid solutions than with colloid‐based solutions. This study examined the combination of initial histidine‐tryptophan‐ketoglutarate solution (HTK) graft flush and subsequent storage in University of Wisconsin solution (UW) to that of the single use of each solution.

Jérôme Dumortier, Mustapha Adham, Charles Ber, Catherine Boucaud, Yves Bouffard, Bertrand Delafosse, Pierre Sagnard, Olivier Boillot – 9 October 2006 – While the number of candidates for liver transplantation has increased in the recent years, the pool of cadaveric donor organs has remained constant and the waiting time progressively increases. These facts led us to start a program of adult‐to‐adult living‐donor liver transplantation in 1998. The aim of this study was to compare the outcome of all patients put on the waiting list since 1998.

Alberto Grassi, Chiara Quarneti, Matteo Ravaioli, Francesco Bianchini, Micaela Susca, Antonia D'Errico, Fabio Piscaglia, Maria Rosa Tamè, Pietro Andreone, GianLuca Grazi, Silvia Galli, Daniela Zauli, Antonio D. Pinna, Francesco B. Bianchi, Giorgio Ballardini – 9 October 2006 – The aim of this study was to evaluate how the immunohistochemical detection of liver hepatitis C virus (HCV) antigens (HCV‐Ag) could support the histologic diagnosis and influence the clinical management of post‐liver transplantation (LT) liver disease.