Sphingosine 1‐phosphate protects rat liver sinusoidal endothelial cells from ethanol‐induced apoptosis: Role of intracellular calcium and nitric oxide
Dong‐Mei Zheng, Tsuneo Kitamura, Kenichi Ikejima, Nobuyuki Enomoto, Shunhei Yamashina, Satoko Suzuki, Yoshiyuki Takei, Nobuhiro Sato – 20 October 2006 – In alcoholic liver disease, ethanol‐induced damage to sinusoidal endothelial cells (SECs) appears to be important in the progression of liver damage. However, little is known about the mechanisms responsible for protection of SECs against ethanol‐induced injury.