Characterization of human liver dendritic cells in liver grafts and perfusates
Brenda M. Bosma, Herold J. Metselaar, Shanta Mancham, Partrick P.C. Boor, Johannes G. Kusters, Geert Kazemier, Hugo W. Tilanus, Ernst J. Kuipers, Jaap Kwekkeboom – 23 February 2006 – It is generally accepted that donor myeloid dendritic cells (MDC) are the main instigators of acute rejection after organ transplantation. The aim of the present study was to characterize MDC in human donor livers using liver grafts and perfusates as a source. Perfusates were collected during ex vivo vascular perfusion of liver grafts pretransplantation.